Extracellular release of virulence factor major surface protease via exosomes in Leishmania infantum promastigotes

Extracellular release of virulence factor major surface protease via exosomes in Leishmania infantum promastigotes

Abstract Background The Leishmania spp. protozoa are introduced into humans through a sand fly blood meal, depositing the infectious metacyclic promastigote form of the parasite into human skin. Parasites enter a variety of host cells, although a majority are found in macrophages where they replicat...

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Bibliographic Details
Main Authors: Skye Marshall, Patrick H. Kelly, Brajesh K. Singh, R. Marshall Pope, Peter Kim, Bayan Zhanbolat, Mary E. Wilson, Chaoqun Yao
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Parasites & Vectors
Subjects:
Leishmania
Exosome
Major surface protease
Virulence factors
Promastigotes
Online Access:http://link.springer.com/article/10.1186/s13071-018-2937-y

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