Association of miRNA122 & ADAM17 with lipids among hypertensives in Nigeria

Dyslipidaemia and hypertension are established major risk factors for cardiovascular diseases. The suggested roles of miRNA-122 and ADAM17 in lipid metabolism can therefore be applied in the management of metabolic disorders. The authors’ aim was to determine the association between miRNA-122 and AD...

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Main Authors: Meka Ijeoma A., Anyim Obumneme B., Enebe Joseph T., Ukwaja Kingsley N., Ugonabo Martin C.
Format: Article
Language:English
Published: De Gruyter 2018-09-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2018-0053
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author Meka Ijeoma A.
Anyim Obumneme B.
Enebe Joseph T.
Ukwaja Kingsley N.
Ugonabo Martin C.
author_facet Meka Ijeoma A.
Anyim Obumneme B.
Enebe Joseph T.
Ukwaja Kingsley N.
Ugonabo Martin C.
author_sort Meka Ijeoma A.
collection DOAJ
description Dyslipidaemia and hypertension are established major risk factors for cardiovascular diseases. The suggested roles of miRNA-122 and ADAM17 in lipid metabolism can therefore be applied in the management of metabolic disorders. The authors’ aim was to determine the association between miRNA-122 and ADAM17, as well as the association between miRNA-122 and lipid fractions, in the study participants.
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spelling doaj.art-7daa0576260d424c86b0c0521fd7cd952022-12-21T21:47:19ZengDe GruyterOpen Medicine2391-54632018-09-0113135035810.1515/med-2018-0053med-2018-0053Association of miRNA122 & ADAM17 with lipids among hypertensives in NigeriaMeka Ijeoma A.0Anyim Obumneme B.1Enebe Joseph T.2Ukwaja Kingsley N.3Ugonabo Martin C.4Department of Chemical Pathology, University of NigeriaEnugu Campus, Enugu, NigeriaDepartment of Internal Medicine, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Enugu, NigeriaDepartment of Obstetrics and Gynaecology, Enugu State University of Science and Technology, Enugu State, Enugu, NigeriaDepartment of Internal Medicine, Federal Teaching Hospital Abakaliki, Ebonyi State, Enugu, NigeriaDepartment of Chemical Pathology, University of NigeriaEnugu Campus, Enugu State, Enugu, NigeriaDyslipidaemia and hypertension are established major risk factors for cardiovascular diseases. The suggested roles of miRNA-122 and ADAM17 in lipid metabolism can therefore be applied in the management of metabolic disorders. The authors’ aim was to determine the association between miRNA-122 and ADAM17, as well as the association between miRNA-122 and lipid fractions, in the study participants.https://doi.org/10.1515/med-2018-0053mirna-122adam17lipidshypertensiondyslipidaemia
spellingShingle Meka Ijeoma A.
Anyim Obumneme B.
Enebe Joseph T.
Ukwaja Kingsley N.
Ugonabo Martin C.
Association of miRNA122 & ADAM17 with lipids among hypertensives in Nigeria
Open Medicine
mirna-122
adam17
lipids
hypertension
dyslipidaemia
title Association of miRNA122 & ADAM17 with lipids among hypertensives in Nigeria
title_full Association of miRNA122 & ADAM17 with lipids among hypertensives in Nigeria
title_fullStr Association of miRNA122 & ADAM17 with lipids among hypertensives in Nigeria
title_full_unstemmed Association of miRNA122 & ADAM17 with lipids among hypertensives in Nigeria
title_short Association of miRNA122 & ADAM17 with lipids among hypertensives in Nigeria
title_sort association of mirna122 adam17 with lipids among hypertensives in nigeria
topic mirna-122
adam17
lipids
hypertension
dyslipidaemia
url https://doi.org/10.1515/med-2018-0053
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