Hypoalbuminemia and risk of death in critically ill patients in a polyvalent unit
Introduction: Hypoalbuminemia can develop in the first hours after an acute illness, and is closely related to an active inflammatory state, regardless of the patient's nutritional status. It has been associated with hospital mortality in patients with post-surgical complications, patients wit...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Spanish |
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ECIMED
2023-03-01
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| Series: | Revista Cubana de Medicina Militar |
| Subjects: | |
| Online Access: | https://revmedmilitar.sld.cu/index.php/mil/article/view/2319 |
| _version_ | 1797870043703279616 |
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| author | Giovanna Silvia Quispe Alarcón Yanín Díaz Lara Jorge Soneira Pérez Sergio González García Hedgar Berty Gutiérrez |
| author_facet | Giovanna Silvia Quispe Alarcón Yanín Díaz Lara Jorge Soneira Pérez Sergio González García Hedgar Berty Gutiérrez |
| author_sort | Giovanna Silvia Quispe Alarcón |
| collection | DOAJ |
| description | Introduction: Hypoalbuminemia can develop in the first hours after an acute illness, and is closely related to an active inflammatory state, regardless of the patient's nutritional status. It has been associated with hospital mortality in patients with post-surgical complications, patients with sepsis and trauma.
Objective: To evaluate the association between hypoalbuminemia level and the risk of mortality in critically ill patients in a polyvalent unit.
Methods: Observational, descriptive, prospective, case series study, with 216 patients admitted to the unit. Demographic, clinical, and laboratory variables were analyzed and the APACHE II prognostic score was applied. Albumin concentration is calculated on admission and hypoalbuminemia is classified as mild (30-35 g/L) and moderate/severe (≤ 30 g/L).
Results: In the study, 28 patients died, which represented 13% of the total number of patients admitted. Albumin levels were low in 118 patients (54.6%), and of these 66 patients (56%) were classified as hypoalbuminemia moderate/severe, with albumin values below 30 g/L. Patients with moderate-severe hypoalbuminemia had a higher risk of death (23.5%) than those patients with levels classified as mild (15.3%), a statistically significant difference (p= 0.034); and in the group of patients with moderate-severe hypoalbuminemia, 67% died, in relation to 33% of patients with levels classified as mild.
Conclusions: Moderate-severe hypoalbuminemia is associated with mortality risk, regardless of admission diagnosis. |
| first_indexed | 2024-04-10T00:22:12Z |
| format | Article |
| id | doaj.art-7daac69820cc43abaf6c84a4c379abd5 |
| institution | Directory Open Access Journal |
| issn | 1561-3046 |
| language | Spanish |
| last_indexed | 2024-04-10T00:22:12Z |
| publishDate | 2023-03-01 |
| publisher | ECIMED |
| record_format | Article |
| series | Revista Cubana de Medicina Militar |
| spelling | doaj.art-7daac69820cc43abaf6c84a4c379abd52023-03-15T22:06:37ZspaECIMEDRevista Cubana de Medicina Militar1561-30462023-03-01521e02302319e02302319739Hypoalbuminemia and risk of death in critically ill patients in a polyvalent unitGiovanna Silvia Quispe Alarcón0Yanín Díaz Lara1Jorge Soneira Pérez2Sergio González García3Hedgar Berty Gutiérrez4Hospital Docente Clínico Quirúrgico ¨Dr. Miguel Enríquez¨Hospital Docente Clínico Quirúrgico ¨Dr. Miguel Enríquez¨Hospital Docente Clínico Quirúrgico ¨Dr. Miguel Enríquez¨Facultad de Ciencias Médicas “Miguel Enríquez”Hospital Docente Clínico Quirúrgico ¨Dr. Miguel Enríquez¨Introduction: Hypoalbuminemia can develop in the first hours after an acute illness, and is closely related to an active inflammatory state, regardless of the patient's nutritional status. It has been associated with hospital mortality in patients with post-surgical complications, patients with sepsis and trauma. Objective: To evaluate the association between hypoalbuminemia level and the risk of mortality in critically ill patients in a polyvalent unit. Methods: Observational, descriptive, prospective, case series study, with 216 patients admitted to the unit. Demographic, clinical, and laboratory variables were analyzed and the APACHE II prognostic score was applied. Albumin concentration is calculated on admission and hypoalbuminemia is classified as mild (30-35 g/L) and moderate/severe (≤ 30 g/L). Results: In the study, 28 patients died, which represented 13% of the total number of patients admitted. Albumin levels were low in 118 patients (54.6%), and of these 66 patients (56%) were classified as hypoalbuminemia moderate/severe, with albumin values below 30 g/L. Patients with moderate-severe hypoalbuminemia had a higher risk of death (23.5%) than those patients with levels classified as mild (15.3%), a statistically significant difference (p= 0.034); and in the group of patients with moderate-severe hypoalbuminemia, 67% died, in relation to 33% of patients with levels classified as mild. Conclusions: Moderate-severe hypoalbuminemia is associated with mortality risk, regardless of admission diagnosis.https://revmedmilitar.sld.cu/index.php/mil/article/view/2319hipoalbuminemiaapache iiriesgo de muertecuidados intensivospaciente crítico. |
| spellingShingle | Giovanna Silvia Quispe Alarcón Yanín Díaz Lara Jorge Soneira Pérez Sergio González García Hedgar Berty Gutiérrez Hypoalbuminemia and risk of death in critically ill patients in a polyvalent unit Revista Cubana de Medicina Militar hipoalbuminemia apache ii riesgo de muerte cuidados intensivos paciente crítico. |
| title | Hypoalbuminemia and risk of death in critically ill patients in a polyvalent unit |
| title_full | Hypoalbuminemia and risk of death in critically ill patients in a polyvalent unit |
| title_fullStr | Hypoalbuminemia and risk of death in critically ill patients in a polyvalent unit |
| title_full_unstemmed | Hypoalbuminemia and risk of death in critically ill patients in a polyvalent unit |
| title_short | Hypoalbuminemia and risk of death in critically ill patients in a polyvalent unit |
| title_sort | hypoalbuminemia and risk of death in critically ill patients in a polyvalent unit |
| topic | hipoalbuminemia apache ii riesgo de muerte cuidados intensivos paciente crítico. |
| url | https://revmedmilitar.sld.cu/index.php/mil/article/view/2319 |
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