Design, Synthesis, and Preliminary Evaluation for Ti-Mo-Zr-Ta-Si Alloys for Potential Implant Applications

Considering the future trends of biomaterials, current studies are focused on the corrosion resistance and the mechanical properties of new materials that need to be considered in the process of strengthening alloys with additive non-toxic elements. Many kinds of titanium alloys with different bioco...

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Main Authors: Madalina Simona Baltatu, Mihaela Claudia Spataru, Liliana Verestiuc, Vera Balan, Carmen Solcan, Andrei Victor Sandu, Victor Geanta, Ionelia Voiculescu, Petrica Vizureanu
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/14/22/6806
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author Madalina Simona Baltatu
Mihaela Claudia Spataru
Liliana Verestiuc
Vera Balan
Carmen Solcan
Andrei Victor Sandu
Victor Geanta
Ionelia Voiculescu
Petrica Vizureanu
author_facet Madalina Simona Baltatu
Mihaela Claudia Spataru
Liliana Verestiuc
Vera Balan
Carmen Solcan
Andrei Victor Sandu
Victor Geanta
Ionelia Voiculescu
Petrica Vizureanu
author_sort Madalina Simona Baltatu
collection DOAJ
description Considering the future trends of biomaterials, current studies are focused on the corrosion resistance and the mechanical properties of new materials that need to be considered in the process of strengthening alloys with additive non-toxic elements. Many kinds of titanium alloys with different biocompatible elements (Mo, Si, Zr, etc.,) have been recently developed for their similar properties with human bone. Four new different alloys were obtained and investigated regarding their microstructure, mechanical, chemical, and biological behavior (in vitro and in vivo evaluation), the alloys are as follows: Ti15Mo7Zr15Ta, Ti15Mo7Zr15Ta0.5Si, Ti15Mo7Zr15Ta0.75Si, and Ti15Mo7Zr15Ta1Si. There were changes with the addition of the silicon element such as the hardness and the modulus of elasticity increased. An MTT assay confirmed the in vitro cytocompatibility of the prepared alloys.
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spelling doaj.art-7daed543673848aeb7d92b8839875fb32023-11-23T00:09:04ZengMDPI AGMaterials1996-19442021-11-011422680610.3390/ma14226806Design, Synthesis, and Preliminary Evaluation for Ti-Mo-Zr-Ta-Si Alloys for Potential Implant ApplicationsMadalina Simona Baltatu0Mihaela Claudia Spataru1Liliana Verestiuc2Vera Balan3Carmen Solcan4Andrei Victor Sandu5Victor Geanta6Ionelia Voiculescu7Petrica Vizureanu8Department of Technologies and Equipments for Materials Processing, Faculty of Materials Science and Engineering, Gheorghe Asachi Technical University of Iaşi, Blvd. Mangeron, No. 51, 700050 Iasi, RomaniaPublic Health Department, Faculty of Veterinary Medicine, “Ion Ionescu de la Brad” University of Life Sciences, 3 Mihail Sadoveanu Alley, 700490 Iasi, RomaniaBiomedical Sciences Department, Faculty of Medical Bioengineering, Grigore T. Popa University of Medicine and Pharmacy, 9-13 Kogalniceanu Street, 700454 Iasi, RomaniaBiomedical Sciences Department, Faculty of Medical Bioengineering, Grigore T. Popa University of Medicine and Pharmacy, 9-13 Kogalniceanu Street, 700454 Iasi, RomaniaPreclinics Department, Faculty of Veterinary Medicine, “Ion Ionescu de la Brad” University of Life Sciences, 3 Mihail Sadoveanu Alley, 700490 Iasi, RomaniaDepartment of Technologies and Equipments for Materials Processing, Faculty of Materials Science and Engineering, Gheorghe Asachi Technical University of Iaşi, Blvd. Mangeron, No. 51, 700050 Iasi, RomaniaEngineering and Management of Metallic Material Processing Department, Faculty of Materials Science and Engineering, University Politehnica of Bucharest, 313 Spl Independentei, 060042 Bucharest, RomaniaQuality Engineering and Industrial Technologies Department, Faculty of Industrial Engineering and Robotics, University Politehnica of Bucharest, 313 Spl Independentei, 060042 Bucharest, RomaniaDepartment of Technologies and Equipments for Materials Processing, Faculty of Materials Science and Engineering, Gheorghe Asachi Technical University of Iaşi, Blvd. Mangeron, No. 51, 700050 Iasi, RomaniaConsidering the future trends of biomaterials, current studies are focused on the corrosion resistance and the mechanical properties of new materials that need to be considered in the process of strengthening alloys with additive non-toxic elements. Many kinds of titanium alloys with different biocompatible elements (Mo, Si, Zr, etc.,) have been recently developed for their similar properties with human bone. Four new different alloys were obtained and investigated regarding their microstructure, mechanical, chemical, and biological behavior (in vitro and in vivo evaluation), the alloys are as follows: Ti15Mo7Zr15Ta, Ti15Mo7Zr15Ta0.5Si, Ti15Mo7Zr15Ta0.75Si, and Ti15Mo7Zr15Ta1Si. There were changes with the addition of the silicon element such as the hardness and the modulus of elasticity increased. An MTT assay confirmed the in vitro cytocompatibility of the prepared alloys.https://www.mdpi.com/1996-1944/14/22/6806titanium alloysobtainingTiMoZrTaSi systemosseointegration
spellingShingle Madalina Simona Baltatu
Mihaela Claudia Spataru
Liliana Verestiuc
Vera Balan
Carmen Solcan
Andrei Victor Sandu
Victor Geanta
Ionelia Voiculescu
Petrica Vizureanu
Design, Synthesis, and Preliminary Evaluation for Ti-Mo-Zr-Ta-Si Alloys for Potential Implant Applications
Materials
titanium alloys
obtaining
TiMoZrTaSi system
osseointegration
title Design, Synthesis, and Preliminary Evaluation for Ti-Mo-Zr-Ta-Si Alloys for Potential Implant Applications
title_full Design, Synthesis, and Preliminary Evaluation for Ti-Mo-Zr-Ta-Si Alloys for Potential Implant Applications
title_fullStr Design, Synthesis, and Preliminary Evaluation for Ti-Mo-Zr-Ta-Si Alloys for Potential Implant Applications
title_full_unstemmed Design, Synthesis, and Preliminary Evaluation for Ti-Mo-Zr-Ta-Si Alloys for Potential Implant Applications
title_short Design, Synthesis, and Preliminary Evaluation for Ti-Mo-Zr-Ta-Si Alloys for Potential Implant Applications
title_sort design synthesis and preliminary evaluation for ti mo zr ta si alloys for potential implant applications
topic titanium alloys
obtaining
TiMoZrTaSi system
osseointegration
url https://www.mdpi.com/1996-1944/14/22/6806
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