Plasmablastic lymphoma as a rare cause of subocclusive events: Case report and review of the literature
Introduction. The most common causes of subocclusive disorders are the adhesion, Crohn's disease and small bowel neoplasms. Plasmablastic lymphoma (PBL) is an aggressive distinct subtype of diffuse large B-cell non-Hodgkin lymphoma initially reported in the oral cavity of the HIV infected indiv...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2019-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501800024L.pdf |
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| author | Lukić Snežana Dragašević Sanja Zgradić Sanja Todorović Milena Đuranović Srđan Anđelić Boško Popović Dragan |
| author_facet | Lukić Snežana Dragašević Sanja Zgradić Sanja Todorović Milena Đuranović Srđan Anđelić Boško Popović Dragan |
| author_sort | Lukić Snežana |
| collection | DOAJ |
| description | Introduction. The most common causes of subocclusive disorders are the adhesion, Crohn's disease and small bowel neoplasms. Plasmablastic lymphoma (PBL) is an aggressive distinct subtype of diffuse large B-cell non-Hodgkin lymphoma initially reported in the oral cavity of the HIV infected individuals. Case report. We presented a male patient with PBL of the small intestine as a rare cause of intestinal subocclusion, without HIV infection and negative serology for hepatitis C, hepatitis B, and Epstein-Barr infection. A 73-year-old male was admitted to our Center due to the one-year history of abdominal pain, weigh loss, non-bloody diarrhea, night sweating and pruritus. The patient underwent the ileocolonoscopic examination with the accompanying biopsy specimens. The results, based on the histopathological and immunohistochemical pattern, confirmed a diagnosis of PBL. Following the chemotherapy treatment, our patient underwent the resection of ileum. The postoperative histopathological report confirmed PBL as the final diagnosis. The patient was treated for the following 6 months with the chemotherapy according to the cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) protocol. Fatal outcome was due to acute myocardial infarct. Conclusion. PBL of the small intestine is a rare and unusual cause of subocclusive events. In our patient, an accurate histopathological verification of the detected changes in the ileum was of crucial importance for further treatment. [Project of the Serbian Ministry of Education, Science and Technological
Development, Grant no. III4100] |
| first_indexed | 2024-12-23T10:05:04Z |
| format | Article |
| id | doaj.art-7db1af3f8b5a4b4a8e43318c5514a5e1 |
| institution | Directory Open Access Journal |
| issn | 0042-8450 2406-0720 |
| language | English |
| last_indexed | 2024-12-23T10:05:04Z |
| publishDate | 2019-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-7db1af3f8b5a4b4a8e43318c5514a5e12022-12-21T17:51:07ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502406-07202019-01-0176121297130010.2298/VSP171025024L0042-84501800024LPlasmablastic lymphoma as a rare cause of subocclusive events: Case report and review of the literatureLukić Snežana0Dragašević Sanja1Zgradić Sanja2Todorović Milena3Đuranović Srđan4Anđelić Boško5Popović Dragan6University of Belgrade, Faculty of Medicine, Belgrade, Serbia + Clinical Center of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade, SerbiaClinical Center of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade, SerbiaClinical Center of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + Clinical Center of Serbia, Clinic for Hematology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + Clinical Center of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + Clinical Center of Serbia, Clinic for Hematology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + Clinical Center of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade, SerbiaIntroduction. The most common causes of subocclusive disorders are the adhesion, Crohn's disease and small bowel neoplasms. Plasmablastic lymphoma (PBL) is an aggressive distinct subtype of diffuse large B-cell non-Hodgkin lymphoma initially reported in the oral cavity of the HIV infected individuals. Case report. We presented a male patient with PBL of the small intestine as a rare cause of intestinal subocclusion, without HIV infection and negative serology for hepatitis C, hepatitis B, and Epstein-Barr infection. A 73-year-old male was admitted to our Center due to the one-year history of abdominal pain, weigh loss, non-bloody diarrhea, night sweating and pruritus. The patient underwent the ileocolonoscopic examination with the accompanying biopsy specimens. The results, based on the histopathological and immunohistochemical pattern, confirmed a diagnosis of PBL. Following the chemotherapy treatment, our patient underwent the resection of ileum. The postoperative histopathological report confirmed PBL as the final diagnosis. The patient was treated for the following 6 months with the chemotherapy according to the cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) protocol. Fatal outcome was due to acute myocardial infarct. Conclusion. PBL of the small intestine is a rare and unusual cause of subocclusive events. In our patient, an accurate histopathological verification of the detected changes in the ileum was of crucial importance for further treatment. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. III4100]http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501800024L.pdfcrohn diseasediagnosis, differentialimmunohistochemistryintestinal neoplasmsintestinal obstructionlymphoma, large b-cell, diffuseplasmablastic lymphomatreatment outcome |
| spellingShingle | Lukić Snežana Dragašević Sanja Zgradić Sanja Todorović Milena Đuranović Srđan Anđelić Boško Popović Dragan Plasmablastic lymphoma as a rare cause of subocclusive events: Case report and review of the literature Vojnosanitetski Pregled crohn disease diagnosis, differential immunohistochemistry intestinal neoplasms intestinal obstruction lymphoma, large b-cell, diffuse plasmablastic lymphoma treatment outcome |
| title | Plasmablastic lymphoma as a rare cause of subocclusive events: Case report and review of the literature |
| title_full | Plasmablastic lymphoma as a rare cause of subocclusive events: Case report and review of the literature |
| title_fullStr | Plasmablastic lymphoma as a rare cause of subocclusive events: Case report and review of the literature |
| title_full_unstemmed | Plasmablastic lymphoma as a rare cause of subocclusive events: Case report and review of the literature |
| title_short | Plasmablastic lymphoma as a rare cause of subocclusive events: Case report and review of the literature |
| title_sort | plasmablastic lymphoma as a rare cause of subocclusive events case report and review of the literature |
| topic | crohn disease diagnosis, differential immunohistochemistry intestinal neoplasms intestinal obstruction lymphoma, large b-cell, diffuse plasmablastic lymphoma treatment outcome |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501800024L.pdf |
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