Adiponectin is protective against endoplasmic reticulum stress-induced apoptosis of endothelial cells in sepsis

Adiponectin is protective against endoplasmic reticulum stress-induced apoptosis of endothelial cells in sepsis

Endoplasmic reticulum (ER) stress is a critical molecular mechanism involved in the pathogenesis of sepsis. Hence, strategies for alleviating this stress may be essential for preventing cardiovascular injuries under sepsis. Adiponectin is secreted by adipocytes and its levels are decreased in sepsis...

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Bibliographic Details
Main Authors: Yun Hou, Xi Feng Wang, Zhi Qiang Lang, Yin Chuan Jin, Jia Rong Fu, Xiao Min Xv, Shi Tian Sun, Xin Xin, Lian Shuang Zhang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Adiponectin
Apoptosis
Endoplasmic reticulum stress
Endothelial cell
Sepsis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001200609&lng=en&tlng=en

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