GDF15 Contributes to the Regulation of the Mechanosensitive Responses of PdL Fibroblasts through the Modulation of IL-37

GDF15 Contributes to the Regulation of the Mechanosensitive Responses of PdL Fibroblasts through the Modulation of IL-37

During orthodontic tooth movement (OTM), areas of compressive and tensile forces are generated in the periodontal ligament (PdL), a mechanoreactive connective tissue between the teeth and alveolar bone. Mechanically stimulated PdL fibroblasts (PdLFs), the main cell type of PdL, express significantly...

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Bibliographic Details
Main Authors: Julia Steinmetz, Albert Stemmler, Christoph-Ludwig Hennig, Judit Symmank, Collin Jacobs
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Dentistry Journal
Subjects:
GDF15
IL-37
periodontal ligament fibroblasts
orthodontic tooth movement
tension
Online Access:https://www.mdpi.com/2304-6767/12/2/39

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