Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers such as DNA

Abstract Biopolymer topology is critical for determining interactions inside cell environments, exemplified by DNA where its response to mechanical perturbation is as important as biochemical properties to its cellular roles. The dynamic structures of chiral biopolymers exhibit complex dependence wi...

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Bibliographic Details
Main Authors: Jack W. Shepherd, Sebastien Guilbaud, Zhaokun Zhou, Jamieson A. L. Howard, Matthew Burman, Charley Schaefer, Adam Kerrigan, Clare Steele-King, Agnes Noy, Mark C. Leake
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-47126-6