Immunotherapy for the elderly. Maybe the best option for lung cancer?
Lung cancer is usually diagnosed at advanced stage and systematic therapy is administered. New current diagnostic techniques such as the convex-endobronchial ultrasound, radial endobronchial ultrasound, cone beam ct, electromagnetic navigation and robotic bronchoscopy provide us with a high diagnost...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Cancer Treatment and Research Communications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468294223000849 |
| _version_ | 1797387804568715264 |
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| author | Paul Zarogoulidis Dimitris Matthaios Panagoula Oikonomou Christina Nikolaou Charalampos Charalampidis Chrysanthi Sardeli |
| author_facet | Paul Zarogoulidis Dimitris Matthaios Panagoula Oikonomou Christina Nikolaou Charalampos Charalampidis Chrysanthi Sardeli |
| author_sort | Paul Zarogoulidis |
| collection | DOAJ |
| description | Lung cancer is usually diagnosed at advanced stage and systematic therapy is administered. New current diagnostic techniques such as the convex-endobronchial ultrasound, radial endobronchial ultrasound, cone beam ct, electromagnetic navigation and robotic bronchoscopy provide us with a high diagnostic yield. These techniques are minimal invasive and patients with comorbidities such as chronic obstructive pulmonary disease and heart failure can be diagnosed with minimal adverse effects. All these techniques provide sufficient sample for molecular investigation. Since immunotherapy was first administered, we have more and more information regarding the appropriate patient target group. Several published studies divided patients as elderly ≥75 and non-elderly ≤74 and investigated the adverse effects of different drugs and survival. In our current commentary we present information on patients receiving immunotherapy versus chemoimmunotherapy in two groups of elderly and non-elderly. Elderly patients can receive both combinations without differences between the two groups, however; more studies are needed to clarify certain aspects. |
| first_indexed | 2024-03-08T22:31:26Z |
| format | Article |
| id | doaj.art-7db7c836f1b54fc4a9145fee825f4534 |
| institution | Directory Open Access Journal |
| issn | 2468-2942 |
| language | English |
| last_indexed | 2024-03-08T22:31:26Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cancer Treatment and Research Communications |
| spelling | doaj.art-7db7c836f1b54fc4a9145fee825f45342023-12-18T04:24:42ZengElsevierCancer Treatment and Research Communications2468-29422023-01-0137100762Immunotherapy for the elderly. Maybe the best option for lung cancer?Paul Zarogoulidis0Dimitris Matthaios1Panagoula Oikonomou2Christina Nikolaou3Charalampos Charalampidis4Chrysanthi Sardeli5Pulmonary Department, General Clinic Euromedica, Thessaloniki, Greece; 3rd University Surgery Department, ``AHEPA`` University Hospital, Thessaloniki, Greece; Corresponding author at: Pulmonary Department, General Clinic Euromedica, Thessaloniki, Greece.Oncology Department, General Hospital of Rhodes, GreeceSurgery Department, Democritus University of Thrace, Alexandroupolis, GreeceSurgery Department, Democritus University of Thrace, Alexandroupolis, GreeceDepartment of Pathology, University of Cyprus, CyprusDepartment of Pharmacology & Clinical Pharmacology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, GreeceLung cancer is usually diagnosed at advanced stage and systematic therapy is administered. New current diagnostic techniques such as the convex-endobronchial ultrasound, radial endobronchial ultrasound, cone beam ct, electromagnetic navigation and robotic bronchoscopy provide us with a high diagnostic yield. These techniques are minimal invasive and patients with comorbidities such as chronic obstructive pulmonary disease and heart failure can be diagnosed with minimal adverse effects. All these techniques provide sufficient sample for molecular investigation. Since immunotherapy was first administered, we have more and more information regarding the appropriate patient target group. Several published studies divided patients as elderly ≥75 and non-elderly ≤74 and investigated the adverse effects of different drugs and survival. In our current commentary we present information on patients receiving immunotherapy versus chemoimmunotherapy in two groups of elderly and non-elderly. Elderly patients can receive both combinations without differences between the two groups, however; more studies are needed to clarify certain aspects.http://www.sciencedirect.com/science/article/pii/S2468294223000849Non-small cell lung cancerTyrosine kinase inhibitorsChemotherapyEbusRadial-ebusBiopsy |
| spellingShingle | Paul Zarogoulidis Dimitris Matthaios Panagoula Oikonomou Christina Nikolaou Charalampos Charalampidis Chrysanthi Sardeli Immunotherapy for the elderly. Maybe the best option for lung cancer? Cancer Treatment and Research Communications Non-small cell lung cancer Tyrosine kinase inhibitors Chemotherapy Ebus Radial-ebus Biopsy |
| title | Immunotherapy for the elderly. Maybe the best option for lung cancer? |
| title_full | Immunotherapy for the elderly. Maybe the best option for lung cancer? |
| title_fullStr | Immunotherapy for the elderly. Maybe the best option for lung cancer? |
| title_full_unstemmed | Immunotherapy for the elderly. Maybe the best option for lung cancer? |
| title_short | Immunotherapy for the elderly. Maybe the best option for lung cancer? |
| title_sort | immunotherapy for the elderly maybe the best option for lung cancer |
| topic | Non-small cell lung cancer Tyrosine kinase inhibitors Chemotherapy Ebus Radial-ebus Biopsy |
| url | http://www.sciencedirect.com/science/article/pii/S2468294223000849 |
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