Ethyl 2-(3-Methyl-5-oxo-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-ylamino)benzoate
A simple route for synthesis of ethyl 2-(3-methyl-5-oxo-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-ylamino)benzoate is developed. The present work involves condensation of 2-(2-nitrobenzamido)propanoic acid with ethyl anthranillate followed by the H2/Pd/C reduction to give the amino ester which upon hea...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2013-12-01
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| Series: | Molbank |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1422-8599/2013/4/M811 |
| Summary: | A simple route for synthesis of ethyl 2-(3-methyl-5-oxo-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-ylamino)benzoate is developed. The present work involves condensation of 2-(2-nitrobenzamido)propanoic acid with ethyl anthranillate followed by the H2/Pd/C reduction to give the amino ester which upon heating in DMF in the presence of FeCl3 affords the title compound. The structure of the title compound was established on the basis of 1H-NMR, 13C-NMR and mass spectral data. |
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| ISSN: | 1422-8599 |