Treatment of oral submucous fibrosis with local injection of salvia miltiorrhiza combined with triamcinolone ace⁃ tonide: a meta⁃analysis
Objective To evaluate the efficacy of the local injection of Salvia miltiorrhiza combined with triamcino⁃ lone acetonide and triamcinolone acetonide alone in the treatment of oral submucous fibrosis (OSF). Methods A meta⁃ analysis was performed by searching the related literature. Three randomized...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
2018-06-01
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| Series: | 口腔疾病防治 |
| Subjects: | |
| Online Access: | http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2018.06.007 |
| _version_ | 1818969409791721472 |
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| author | LIU Gui , LIU Junjie LI Huiling CUI Lin |
| author_facet | LIU Gui , LIU Junjie LI Huiling CUI Lin |
| author_sort | LIU Gui |
| collection | DOAJ |
| description | Objective To evaluate the efficacy of the local injection of Salvia miltiorrhiza combined with triamcino⁃
lone acetonide and triamcinolone acetonide alone in the treatment of oral submucous fibrosis (OSF). Methods A meta⁃
analysis was performed by searching the related literature. Three randomized controlled trials meeting the inclusion crite⁃
ria were identified. Changes in the Visual Analogue Scale (VAS) score and the degree of mouth opening were included in
172 cases (86 cases in the experimental group and 86 in the control group), and changes in the oral mucosal lesion area
were included in 152 cases (76 cases in the experimental group and 76 in the control group). Changes in the VAS score,
the degree of mouth opening and the oral mucosal lesion area were compared in the context of the local injection of Salvia
miltiorrhiza combined with triamcinolone acetonide and triamcinolone acetonide alone. Results There were no signifi⁃
cant differences between the treatment with Salvia miltiorrhiza combined with triamcinolone acetonide and triamcinolone
acetonide alone in reducing the VAS score (P > 0.05). Salvia miltiorrhiza combined with triamcinolone acetonide resulted
in a greater increase in the degree of mouth opening than did triamcinolone acetonide (P = 0.05). The reduction in the oral
mucosal lesion area induced by Salvia miltiorrhiza combined with triamcinolone acetonide was significantly greater than
that induced by triamcinolone acetonide alone (P < 0.05). Conclusion The local injection of Salvia miltiorrhiza com⁃
bined with triamcinolone acetonide is more effective than triamcinolone acetonide alone in the treatment of OSF. |
| first_indexed | 2024-12-20T14:20:08Z |
| format | Article |
| id | doaj.art-7dbd297c79da42db9310fdf970fa078b |
| institution | Directory Open Access Journal |
| issn | 2096-1456 2096-1456 |
| language | zho |
| last_indexed | 2024-12-20T14:20:08Z |
| publishDate | 2018-06-01 |
| publisher | Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases |
| record_format | Article |
| series | 口腔疾病防治 |
| spelling | doaj.art-7dbd297c79da42db9310fdf970fa078b2022-12-21T19:37:57ZzhoEditorial Department of Journal of Prevention and Treatment for Stomatological Diseases口腔疾病防治2096-14562096-14562018-06-0126637437810.12016/j.issn.2096⁃1456.2018.06.007Treatment of oral submucous fibrosis with local injection of salvia miltiorrhiza combined with triamcinolone ace⁃ tonide: a meta⁃analysisLIU Gui0, LIU Junjie1LI Huiling2CUI Lin3Department of Oral Pathology, Xiangya Stomatological Hospital, Central South UniversityDepartment of Oral Pathology, Xiangya Stomatological Hospital, Central South UniversityDepartment of Oral Pathology, Xiangya Stomatological Hospital, Central South UniversityDepartment of Oral Pathology, Xiangya Stomatological Hospital, Central South UniversityObjective To evaluate the efficacy of the local injection of Salvia miltiorrhiza combined with triamcino⁃ lone acetonide and triamcinolone acetonide alone in the treatment of oral submucous fibrosis (OSF). Methods A meta⁃ analysis was performed by searching the related literature. Three randomized controlled trials meeting the inclusion crite⁃ ria were identified. Changes in the Visual Analogue Scale (VAS) score and the degree of mouth opening were included in 172 cases (86 cases in the experimental group and 86 in the control group), and changes in the oral mucosal lesion area were included in 152 cases (76 cases in the experimental group and 76 in the control group). Changes in the VAS score, the degree of mouth opening and the oral mucosal lesion area were compared in the context of the local injection of Salvia miltiorrhiza combined with triamcinolone acetonide and triamcinolone acetonide alone. Results There were no signifi⁃ cant differences between the treatment with Salvia miltiorrhiza combined with triamcinolone acetonide and triamcinolone acetonide alone in reducing the VAS score (P > 0.05). Salvia miltiorrhiza combined with triamcinolone acetonide resulted in a greater increase in the degree of mouth opening than did triamcinolone acetonide (P = 0.05). The reduction in the oral mucosal lesion area induced by Salvia miltiorrhiza combined with triamcinolone acetonide was significantly greater than that induced by triamcinolone acetonide alone (P < 0.05). Conclusion The local injection of Salvia miltiorrhiza com⁃ bined with triamcinolone acetonide is more effective than triamcinolone acetonide alone in the treatment of OSF.http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2018.06.007Oral submucosal fibrosisMeta⁃analysisSalvia miltiorrhizaTriamcinolone acetonide |
| spellingShingle | LIU Gui , LIU Junjie LI Huiling CUI Lin Treatment of oral submucous fibrosis with local injection of salvia miltiorrhiza combined with triamcinolone ace⁃ tonide: a meta⁃analysis 口腔疾病防治 Oral submucosal fibrosis Meta⁃analysis Salvia miltiorrhiza Triamcinolone acetonide |
| title | Treatment of oral submucous fibrosis with local injection of salvia miltiorrhiza combined with triamcinolone ace⁃ tonide: a meta⁃analysis |
| title_full | Treatment of oral submucous fibrosis with local injection of salvia miltiorrhiza combined with triamcinolone ace⁃ tonide: a meta⁃analysis |
| title_fullStr | Treatment of oral submucous fibrosis with local injection of salvia miltiorrhiza combined with triamcinolone ace⁃ tonide: a meta⁃analysis |
| title_full_unstemmed | Treatment of oral submucous fibrosis with local injection of salvia miltiorrhiza combined with triamcinolone ace⁃ tonide: a meta⁃analysis |
| title_short | Treatment of oral submucous fibrosis with local injection of salvia miltiorrhiza combined with triamcinolone ace⁃ tonide: a meta⁃analysis |
| title_sort | treatment of oral submucous fibrosis with local injection of salvia miltiorrhiza combined with triamcinolone ace⁃ tonide a meta⁃analysis |
| topic | Oral submucosal fibrosis Meta⁃analysis Salvia miltiorrhiza Triamcinolone acetonide |
| url | http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2018.06.007 |
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