A Case of Proliferative Diabetic Retinopathy with HIV Infection in Which HAART Possibly Influenced the Prognosis of Visual Function
Background: We report on a patient with proliferative diabetic retinopathy (PDR) and human immunodeficiency virus (HIV) infection who exhibited extremely active PDR followed by a rapid onset of blindness in the right eye. The progression of visual disturbance in the patient’s left eye was slowed aft...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2016-11-01
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| Series: | Case Reports in Ophthalmology |
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| Online Access: | http://www.karger.com/Article/FullText/452789 |
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| author | Takakuni Kitagaki Takaki Sato Junko Hirai Daisaku Kimura Keigo Kakurai Masanori Fukumoto Kensuke Tajiri Takatoshi Kobayashi Teruyo Kida Shota Kojima Tsunehiko Ikeda |
| author_facet | Takakuni Kitagaki Takaki Sato Junko Hirai Daisaku Kimura Keigo Kakurai Masanori Fukumoto Kensuke Tajiri Takatoshi Kobayashi Teruyo Kida Shota Kojima Tsunehiko Ikeda |
| author_sort | Takakuni Kitagaki |
| collection | DOAJ |
| description | Background: We report on a patient with proliferative diabetic retinopathy (PDR) and human immunodeficiency virus (HIV) infection who exhibited extremely active PDR followed by a rapid onset of blindness in the right eye. The progression of visual disturbance in the patient’s left eye was slowed after starting highly active anti-retroviral therapy (HAART), and vision in that eye was rescued after vitrectomy. Case Report: A 72-year-old male developed pneumocystis carinii pneumonia stemming from an HIV infection and began HAART at the Department of Hematology, Osaka Medical College, Takatsuki City, Japan. Prior to HAART, the patient had shown rapidly progressing retinopathy in the right eye accompanied by vitreous hemorrhage, tractional retinal detachment, and neovascular glaucoma, ultimately leading to early-onset blindness. After starting HAART, the progression of the retinopathy in the left eye became slower compared to the right eye, with corrected visual acuity improving to 0.6 after vitrectomy, despite being accompanied by vitreous hemorrhage. The patient’s overall condition has remained stable following the operation, and the condition of the ocular fundus in the left eye has also settled. Conclusion: Significant differences were found in the progression rate of PDR with HIV infection between before and after starting HAART. Our findings suggest that early administration of HAART to HIV patients with diabetic retinopathy is crucial for maintaining visual function. |
| first_indexed | 2024-04-12T14:13:19Z |
| format | Article |
| id | doaj.art-7dbdd0d381ca40898230069637a55a60 |
| institution | Directory Open Access Journal |
| issn | 1663-2699 |
| language | English |
| last_indexed | 2024-04-12T14:13:19Z |
| publishDate | 2016-11-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Ophthalmology |
| spelling | doaj.art-7dbdd0d381ca40898230069637a55a602022-12-22T03:29:48ZengKarger PublishersCase Reports in Ophthalmology1663-26992016-11-017323924410.1159/000452789452789A Case of Proliferative Diabetic Retinopathy with HIV Infection in Which HAART Possibly Influenced the Prognosis of Visual FunctionTakakuni KitagakiTakaki SatoJunko HiraiDaisaku KimuraKeigo KakuraiMasanori FukumotoKensuke TajiriTakatoshi KobayashiTeruyo KidaShota KojimaTsunehiko IkedaBackground: We report on a patient with proliferative diabetic retinopathy (PDR) and human immunodeficiency virus (HIV) infection who exhibited extremely active PDR followed by a rapid onset of blindness in the right eye. The progression of visual disturbance in the patient’s left eye was slowed after starting highly active anti-retroviral therapy (HAART), and vision in that eye was rescued after vitrectomy. Case Report: A 72-year-old male developed pneumocystis carinii pneumonia stemming from an HIV infection and began HAART at the Department of Hematology, Osaka Medical College, Takatsuki City, Japan. Prior to HAART, the patient had shown rapidly progressing retinopathy in the right eye accompanied by vitreous hemorrhage, tractional retinal detachment, and neovascular glaucoma, ultimately leading to early-onset blindness. After starting HAART, the progression of the retinopathy in the left eye became slower compared to the right eye, with corrected visual acuity improving to 0.6 after vitrectomy, despite being accompanied by vitreous hemorrhage. The patient’s overall condition has remained stable following the operation, and the condition of the ocular fundus in the left eye has also settled. Conclusion: Significant differences were found in the progression rate of PDR with HIV infection between before and after starting HAART. Our findings suggest that early administration of HAART to HIV patients with diabetic retinopathy is crucial for maintaining visual function.http://www.karger.com/Article/FullText/452789Human immunodeficiency virusHIVProliferative diabetic retinopathyPDRVitrectomyHighly active anti-retroviral therapyHAART |
| spellingShingle | Takakuni Kitagaki Takaki Sato Junko Hirai Daisaku Kimura Keigo Kakurai Masanori Fukumoto Kensuke Tajiri Takatoshi Kobayashi Teruyo Kida Shota Kojima Tsunehiko Ikeda A Case of Proliferative Diabetic Retinopathy with HIV Infection in Which HAART Possibly Influenced the Prognosis of Visual Function Case Reports in Ophthalmology Human immunodeficiency virus HIV Proliferative diabetic retinopathy PDR Vitrectomy Highly active anti-retroviral therapy HAART |
| title | A Case of Proliferative Diabetic Retinopathy with HIV Infection in Which HAART Possibly Influenced the Prognosis of Visual Function |
| title_full | A Case of Proliferative Diabetic Retinopathy with HIV Infection in Which HAART Possibly Influenced the Prognosis of Visual Function |
| title_fullStr | A Case of Proliferative Diabetic Retinopathy with HIV Infection in Which HAART Possibly Influenced the Prognosis of Visual Function |
| title_full_unstemmed | A Case of Proliferative Diabetic Retinopathy with HIV Infection in Which HAART Possibly Influenced the Prognosis of Visual Function |
| title_short | A Case of Proliferative Diabetic Retinopathy with HIV Infection in Which HAART Possibly Influenced the Prognosis of Visual Function |
| title_sort | case of proliferative diabetic retinopathy with hiv infection in which haart possibly influenced the prognosis of visual function |
| topic | Human immunodeficiency virus HIV Proliferative diabetic retinopathy PDR Vitrectomy Highly active anti-retroviral therapy HAART |
| url | http://www.karger.com/Article/FullText/452789 |
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