Potential Utility of Natural Killer Cells for Eliminating Cells Harboring Reactivated Latent HIV-1 Following the Removal of CD8<sup>+</sup> T Cell-Mediated Pro-Latency Effect(s)
An impediment to curing HIV-1 infection is the persistence of latently infected cells in ART-treated people living with HIV (PLWH). A key strategy for curing HIV-1 infection is to activate transcription and translation of latent virus using latency reversing agents (LRAs) and eliminate cells harbori...
Main Authors: | Georges Khoury, Deanna A. Kulpa, Matthew S. Parsons |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
|
Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/13/8/1451 |
Similar Items
-
Associations between NK Cells in Different Immune Organs and Cellular SIV DNA and RNA in Regional HLADR<sup>−</sup> CD4<sup>+</sup> T Cells in Chronically SIV<sub>mac239</sub>-Infected, Treatment-Naïve Rhesus Macaques
by: Xinjie Li, et al.
Published: (2022-11-01) -
Editorial: The relevance of molecular mechanisms in HIV-1 latency and reactivation from latency
by: Alexander O. Pasternak, et al.
Published: (2023-04-01) -
HIV Latency in Myeloid Cells: Challenges for a Cure
by: Alisha Chitrakar, et al.
Published: (2022-05-01) -
Corrigendum: Editorial: The relevance of molecular mechanisms in HIV-1 latency and reactivation from latency
by: Alexander O. Pasternak, et al.
Published: (2023-05-01) -
The cell biology of HIV-1 latency and rebound
by: Uri Mbonye, et al.
Published: (2024-04-01)