Phytochemical investigation of methanolic extract of Zataria multiflora Boiss.

Background: Zataria multiflora Boiss. (Lamiaceae) has been found in Iran, Afghanistan, and Pakistan. Z. multiflora called ‘Avishane Shirazi’ in Persian is used as a seasoned in many foods in Iran. The literature survey demonstrated that Z. multiflora has immunostimulant, pain-relieving, antinocicept...

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Main Authors: Emad Nazaryanpour, Samad Nejad Ebrahimi
Format: Article
Language:English
Published: Institue of Medicinal Plants, ACECR 2020-09-01
Series:Journal of Medicinal Plants
Subjects:
Online Access:http://jmp.ir/article-1-2615-en.html
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author Emad Nazaryanpour
Samad Nejad Ebrahimi
author_facet Emad Nazaryanpour
Samad Nejad Ebrahimi
author_sort Emad Nazaryanpour
collection DOAJ
description Background: Zataria multiflora Boiss. (Lamiaceae) has been found in Iran, Afghanistan, and Pakistan. Z. multiflora called ‘Avishane Shirazi’ in Persian is used as a seasoned in many foods in Iran. The literature survey demonstrated that Z. multiflora has immunostimulant, pain-relieving, antinociceptive, anti-inflammatory, antioxidant, antibacterial, antiviral, antiparasitic, antifungal effects and also widely used in traditional medicine for analgesia, diarrhea, infectious diseases, and gastrointestinal problems. Objective: The subject of this study is performing phytochemical constituents of methanolic extract of Z. multiflora. Methods: The application of various chromatographic techniques such as normal and reverse C18 chromatography let to isolation, purification and identification of several flavonoids. Results: In this investigation, the fractionation of methanol extract of the aerial parts of Z. multiflora led to the isolation and purification of three known flavonoid glycosides namely Luteolin 7-O-glucopyranoside, Apigenin 7-O-rutinoside and Luteolin 7-O-rutinoside whose structures were determined by 1D and 2D-NMR spectroscopic studies, in particular, homo-COSY and hetero (HSQC and HMBC). Conclusion: The results show a methanolic extract of Z. multiflora is a rich source of flavonoids and triterpenoids.
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spelling doaj.art-7dbf434a8bd44cb38ed17f6ee80558c92022-12-21T18:35:09ZengInstitue of Medicinal Plants, ACECRJournal of Medicinal Plants2717-204X2717-20582020-09-011975239253Phytochemical investigation of methanolic extract of Zataria multiflora Boiss.Emad Nazaryanpour0Samad Nejad Ebrahimi1 Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University G.C., Tehran, Iran Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University G.C., Tehran, Iran Background: Zataria multiflora Boiss. (Lamiaceae) has been found in Iran, Afghanistan, and Pakistan. Z. multiflora called ‘Avishane Shirazi’ in Persian is used as a seasoned in many foods in Iran. The literature survey demonstrated that Z. multiflora has immunostimulant, pain-relieving, antinociceptive, anti-inflammatory, antioxidant, antibacterial, antiviral, antiparasitic, antifungal effects and also widely used in traditional medicine for analgesia, diarrhea, infectious diseases, and gastrointestinal problems. Objective: The subject of this study is performing phytochemical constituents of methanolic extract of Z. multiflora. Methods: The application of various chromatographic techniques such as normal and reverse C18 chromatography let to isolation, purification and identification of several flavonoids. Results: In this investigation, the fractionation of methanol extract of the aerial parts of Z. multiflora led to the isolation and purification of three known flavonoid glycosides namely Luteolin 7-O-glucopyranoside, Apigenin 7-O-rutinoside and Luteolin 7-O-rutinoside whose structures were determined by 1D and 2D-NMR spectroscopic studies, in particular, homo-COSY and hetero (HSQC and HMBC). Conclusion: The results show a methanolic extract of Z. multiflora is a rich source of flavonoids and triterpenoids.http://jmp.ir/article-1-2615-en.htmlavishane shiraziphytochemical investigationflavonoidrosmarinic acid
spellingShingle Emad Nazaryanpour
Samad Nejad Ebrahimi
Phytochemical investigation of methanolic extract of Zataria multiflora Boiss.
Journal of Medicinal Plants
avishane shirazi
phytochemical investigation
flavonoid
rosmarinic acid
title Phytochemical investigation of methanolic extract of Zataria multiflora Boiss.
title_full Phytochemical investigation of methanolic extract of Zataria multiflora Boiss.
title_fullStr Phytochemical investigation of methanolic extract of Zataria multiflora Boiss.
title_full_unstemmed Phytochemical investigation of methanolic extract of Zataria multiflora Boiss.
title_short Phytochemical investigation of methanolic extract of Zataria multiflora Boiss.
title_sort phytochemical investigation of methanolic extract of zataria multiflora boiss
topic avishane shirazi
phytochemical investigation
flavonoid
rosmarinic acid
url http://jmp.ir/article-1-2615-en.html
work_keys_str_mv AT emadnazaryanpour phytochemicalinvestigationofmethanolicextractofzatariamultifloraboiss
AT samadnejadebrahimi phytochemicalinvestigationofmethanolicextractofzatariamultifloraboiss