Mechanistic study on the nuclear modifier gene MSS1 mutation suppressing neomycin sensitivity of the mitochondrial 15S rRNA C1477G mutation in Saccharomyces cerevisiae.

Mechanistic study on the nuclear modifier gene MSS1 mutation suppressing neomycin sensitivity of the mitochondrial 15S rRNA C1477G mutation in Saccharomyces cerevisiae.

The phenotypic manifestation of mitochondrial DNA (mtDNA) mutations can be modulated by nuclear genes and environmental factors. However, neither the interaction among these factors nor their underlying mechanisms are well understood. The yeast Saccharomyces cerevisiae mtDNA 15S rRNA C1477G mutation...

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Bibliographic Details
Main Authors: Qiyin Zhou, Wei Wang, Xiangyu He, Xiaoyu Zhu, Yaoyao Shen, Zhe Yu, Xuexiang Wang, Xuchen Qi, Xuan Zhang, Mingjie Fan, Yu Dai, Shuxu Yang, Qingfeng Yan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3940847?pdf=render

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