An active surveillance program in oral preneoplasia and translational oncology benefit
Abstract Objective We desired to establish an active surveillance clinic for head and neck cancer. In this review we examined. Methods We examined the natural history of human oral carcinogenesis, the types of preneoplastic lesions, and efforts at oral chemoprevention over the past decades for prese...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-08-01
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| Series: | Laryngoscope Investigative Otolaryngology |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/lio2.612 |
| _version_ | 1818655020856377344 |
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| author | Hunter Archibald Seth Buryska Frank G. Ondrey |
| author_facet | Hunter Archibald Seth Buryska Frank G. Ondrey |
| author_sort | Hunter Archibald |
| collection | DOAJ |
| description | Abstract Objective We desired to establish an active surveillance clinic for head and neck cancer. In this review we examined. Methods We examined the natural history of human oral carcinogenesis, the types of preneoplastic lesions, and efforts at oral chemoprevention over the past decades for presentation here. Results We established a clinic and program for patients with oral premalignant lesions approximately over 15 years ago based on an unmetneed for this service. We have completed over 4000 outpatient visits for this cohort and have a place for referrals of difficult oral lesions. We have leveraged this population for multiple federally funded trials on oral cancer prevention as well as specimen banking. Conclusion There is need for routine active surveillance for oral preneoplastic conditions in patients at high risk for conversion to cancer. There are no effective durable treatment or preventions for these individuals and we have attempted to fill this unmet need with our program. |
| first_indexed | 2024-12-17T03:03:03Z |
| format | Article |
| id | doaj.art-7dc6964e5f414df4b883a04f7c170d0b |
| institution | Directory Open Access Journal |
| issn | 2378-8038 |
| language | English |
| last_indexed | 2024-12-17T03:03:03Z |
| publishDate | 2021-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Laryngoscope Investigative Otolaryngology |
| spelling | doaj.art-7dc6964e5f414df4b883a04f7c170d0b2022-12-21T22:06:01ZengWileyLaryngoscope Investigative Otolaryngology2378-80382021-08-016476477210.1002/lio2.612An active surveillance program in oral preneoplasia and translational oncology benefitHunter Archibald0Seth Buryska1Frank G. Ondrey2Department of Otolaryngology‐Head and Neck Surgery University of Minnesota Minneapolis Minnesota USAUniversity of Minnesota Medical School University of Minnesota Minneapolis Minnesota USADepartment of Otolaryngology‐Head and Neck Surgery University of Minnesota Minneapolis Minnesota USAAbstract Objective We desired to establish an active surveillance clinic for head and neck cancer. In this review we examined. Methods We examined the natural history of human oral carcinogenesis, the types of preneoplastic lesions, and efforts at oral chemoprevention over the past decades for presentation here. Results We established a clinic and program for patients with oral premalignant lesions approximately over 15 years ago based on an unmetneed for this service. We have completed over 4000 outpatient visits for this cohort and have a place for referrals of difficult oral lesions. We have leveraged this population for multiple federally funded trials on oral cancer prevention as well as specimen banking. Conclusion There is need for routine active surveillance for oral preneoplastic conditions in patients at high risk for conversion to cancer. There are no effective durable treatment or preventions for these individuals and we have attempted to fill this unmet need with our program.https://doi.org/10.1002/lio2.612active surveillanceoral leukoplakiapreneoplasiasquamous cell carcinoma |
| spellingShingle | Hunter Archibald Seth Buryska Frank G. Ondrey An active surveillance program in oral preneoplasia and translational oncology benefit Laryngoscope Investigative Otolaryngology active surveillance oral leukoplakia preneoplasia squamous cell carcinoma |
| title | An active surveillance program in oral preneoplasia and translational oncology benefit |
| title_full | An active surveillance program in oral preneoplasia and translational oncology benefit |
| title_fullStr | An active surveillance program in oral preneoplasia and translational oncology benefit |
| title_full_unstemmed | An active surveillance program in oral preneoplasia and translational oncology benefit |
| title_short | An active surveillance program in oral preneoplasia and translational oncology benefit |
| title_sort | active surveillance program in oral preneoplasia and translational oncology benefit |
| topic | active surveillance oral leukoplakia preneoplasia squamous cell carcinoma |
| url | https://doi.org/10.1002/lio2.612 |
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