Understanding the relationships between physiological and psychosocial stress, cortisol and cognition
Stress is viewed as a state of real or perceived threat to homeostasis, the management of which involves the endocrine, nervous, and immune systems. These systems work independently and interactively as part of the stress response. The scientific stress literature, which spans both animal and human...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1085950/full |
| _version_ | 1811159557728108544 |
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| author | Katharine Ann James Katharine Ann James Juliet Ilena Stromin Nina Steenkamp Marc Irwin Combrinck |
| author_facet | Katharine Ann James Katharine Ann James Juliet Ilena Stromin Nina Steenkamp Marc Irwin Combrinck |
| author_sort | Katharine Ann James |
| collection | DOAJ |
| description | Stress is viewed as a state of real or perceived threat to homeostasis, the management of which involves the endocrine, nervous, and immune systems. These systems work independently and interactively as part of the stress response. The scientific stress literature, which spans both animal and human studies, contains heterogeneous findings about the effects of stress on the brain and the body. This review seeks to summarise and integrate literature on the relationships between these systems, examining particularly the roles of physiological and psychosocial stress, the stress hormone cortisol, as controlled by the hypothalamic-pituitary-adrenal (HPA) axis, and the effects of stress on cognitive functioning. Health conditions related to impaired HPA axis functioning and their associated neuropsychiatric symptoms will also be considered. Lastly, this review will provide suggestions of clinical applicability for endocrinologists who are uniquely placed to measure outcomes related to endocrine, nervous and immune system functioning and identify areas of intervention. |
| first_indexed | 2024-04-10T05:43:13Z |
| format | Article |
| id | doaj.art-7dccc47f543f427f83d86eaef3e2b8aa |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-10T05:43:13Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-7dccc47f543f427f83d86eaef3e2b8aa2023-03-06T06:37:20ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-03-011410.3389/fendo.2023.10859501085950Understanding the relationships between physiological and psychosocial stress, cortisol and cognitionKatharine Ann James0Katharine Ann James1Juliet Ilena Stromin2Nina Steenkamp3Marc Irwin Combrinck4Applied Cognitive Science and Experimental Neuropsychology Team (ACSENT) Laboratory, Department of Psychology, University of Cape Town, Cape Town, South AfricaDivision of Geriatric Medicine, Department of Medicine, University of Cape Town, Cape Town, South AfricaApplied Cognitive Science and Experimental Neuropsychology Team (ACSENT) Laboratory, Department of Psychology, University of Cape Town, Cape Town, South AfricaApplied Cognitive Science and Experimental Neuropsychology Team (ACSENT) Laboratory, Department of Psychology, University of Cape Town, Cape Town, South AfricaDivision of Geriatric Medicine, Department of Medicine, University of Cape Town, Cape Town, South AfricaStress is viewed as a state of real or perceived threat to homeostasis, the management of which involves the endocrine, nervous, and immune systems. These systems work independently and interactively as part of the stress response. The scientific stress literature, which spans both animal and human studies, contains heterogeneous findings about the effects of stress on the brain and the body. This review seeks to summarise and integrate literature on the relationships between these systems, examining particularly the roles of physiological and psychosocial stress, the stress hormone cortisol, as controlled by the hypothalamic-pituitary-adrenal (HPA) axis, and the effects of stress on cognitive functioning. Health conditions related to impaired HPA axis functioning and their associated neuropsychiatric symptoms will also be considered. Lastly, this review will provide suggestions of clinical applicability for endocrinologists who are uniquely placed to measure outcomes related to endocrine, nervous and immune system functioning and identify areas of intervention.https://www.frontiersin.org/articles/10.3389/fendo.2023.1085950/fullcognitioncortisolendocrinologisthypothalamic - pituitary - adrenal axisglucocorticoidsphysiological stress |
| spellingShingle | Katharine Ann James Katharine Ann James Juliet Ilena Stromin Nina Steenkamp Marc Irwin Combrinck Understanding the relationships between physiological and psychosocial stress, cortisol and cognition Frontiers in Endocrinology cognition cortisol endocrinologist hypothalamic - pituitary - adrenal axis glucocorticoids physiological stress |
| title | Understanding the relationships between physiological and psychosocial stress, cortisol and cognition |
| title_full | Understanding the relationships between physiological and psychosocial stress, cortisol and cognition |
| title_fullStr | Understanding the relationships between physiological and psychosocial stress, cortisol and cognition |
| title_full_unstemmed | Understanding the relationships between physiological and psychosocial stress, cortisol and cognition |
| title_short | Understanding the relationships between physiological and psychosocial stress, cortisol and cognition |
| title_sort | understanding the relationships between physiological and psychosocial stress cortisol and cognition |
| topic | cognition cortisol endocrinologist hypothalamic - pituitary - adrenal axis glucocorticoids physiological stress |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1085950/full |
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