ECG interpretation in Brugada syndrome

Type 1 ST-segment elevation is diagnostic of Brugada syndrome and its presence may be associated with a high risk of arrhythmic events. However, similar changes on electrocardiogram (ECG) are observed in various normal and abnormal conditions. A type 1 ECG can also be unmasked by administration of s...

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Main Authors: Mitsuhiro Nishizaki, MD, Noriyoshi Yamawake, MD, Harumizu Sakurada, MD, Masayasu Hiraoka, MD, FACC
Format: Article
Language:English
Published: Wiley 2013-04-01
Series:Journal of Arrhythmia
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1880427613000057
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author Mitsuhiro Nishizaki, MD
Noriyoshi Yamawake, MD
Harumizu Sakurada, MD
Masayasu Hiraoka, MD, FACC
author_facet Mitsuhiro Nishizaki, MD
Noriyoshi Yamawake, MD
Harumizu Sakurada, MD
Masayasu Hiraoka, MD, FACC
author_sort Mitsuhiro Nishizaki, MD
collection DOAJ
description Type 1 ST-segment elevation is diagnostic of Brugada syndrome and its presence may be associated with a high risk of arrhythmic events. However, similar changes on electrocardiogram (ECG) are observed in various normal and abnormal conditions. A type 1 ECG can also be unmasked by administration of sodium channel blockers in equivocal or suspected cases of Brugada syndrome, and this drug challenge test is frequently used in the diagnosis of symptomatic patients showing non-type 1 ECG patterns. The presence of a transient spontaneous type 1 ECG rather than a drug-induced type I ECG is an important sign for risk prediction of arrhythmia events, even in asymptomatic patients. In asymptomatic individuals, multiple and repeated ECG recordings rather than drug testing are recommended for detecting the transient appearance of a spontaneous type 1 ECG, which may indicate the future development of arrhythmic events. There is little doubt that ECG interpretation, including diagnostic criteria and differential diagnosis, constitutes the hallmark of Brugada syndrome.
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spelling doaj.art-7dcfe01204244f1083165557a973390c2022-12-21T19:47:06ZengWileyJournal of Arrhythmia1880-42762013-04-01292566410.1016/j.joa.2013.01.001ECG interpretation in Brugada syndromeMitsuhiro Nishizaki, MD0Noriyoshi Yamawake, MD1Harumizu Sakurada, MD2Masayasu Hiraoka, MD, FACC3Department of Cardiology, Yokohama Minami Kyosai Hospital, Yokohama, JapanDepartment of Cardiology, Yokohama Minami Kyosai Hospital, Yokohama, JapanTokyo Metropolitan Health and Medical Treatment Corporation Ohkubo Hospital, Tokyo, JapanTokyo Medical and Dental University, Tokyo, JapanType 1 ST-segment elevation is diagnostic of Brugada syndrome and its presence may be associated with a high risk of arrhythmic events. However, similar changes on electrocardiogram (ECG) are observed in various normal and abnormal conditions. A type 1 ECG can also be unmasked by administration of sodium channel blockers in equivocal or suspected cases of Brugada syndrome, and this drug challenge test is frequently used in the diagnosis of symptomatic patients showing non-type 1 ECG patterns. The presence of a transient spontaneous type 1 ECG rather than a drug-induced type I ECG is an important sign for risk prediction of arrhythmia events, even in asymptomatic patients. In asymptomatic individuals, multiple and repeated ECG recordings rather than drug testing are recommended for detecting the transient appearance of a spontaneous type 1 ECG, which may indicate the future development of arrhythmic events. There is little doubt that ECG interpretation, including diagnostic criteria and differential diagnosis, constitutes the hallmark of Brugada syndrome.http://www.sciencedirect.com/science/article/pii/S1880427613000057Brugada syndromeCoved type ST-segment elevationType 1 ECGSudden cardiac deathVentricular fibrillation
spellingShingle Mitsuhiro Nishizaki, MD
Noriyoshi Yamawake, MD
Harumizu Sakurada, MD
Masayasu Hiraoka, MD, FACC
ECG interpretation in Brugada syndrome
Journal of Arrhythmia
Brugada syndrome
Coved type ST-segment elevation
Type 1 ECG
Sudden cardiac death
Ventricular fibrillation
title ECG interpretation in Brugada syndrome
title_full ECG interpretation in Brugada syndrome
title_fullStr ECG interpretation in Brugada syndrome
title_full_unstemmed ECG interpretation in Brugada syndrome
title_short ECG interpretation in Brugada syndrome
title_sort ecg interpretation in brugada syndrome
topic Brugada syndrome
Coved type ST-segment elevation
Type 1 ECG
Sudden cardiac death
Ventricular fibrillation
url http://www.sciencedirect.com/science/article/pii/S1880427613000057
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