Cellular dynamics of EMT: lessons from live in vivo imaging of embryonic development

Cellular dynamics of EMT: lessons from live in vivo imaging of embryonic development

Abstract Epithelial-mesenchymal transition (EMT) refers to a process in which epithelial cells lose apical-basal polarity and loosen cell–cell junctions to take on mesenchymal cell morphologies and invasive properties that facilitate migration through extracellular matrix. EMT—and the reverse mesenc...

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Bibliographic Details
Main Author:	Jeffrey D. Amack
Format:	Article
Language:	English
Published:	BMC 2021-07-01
Series:	Cell Communication and Signaling
Subjects:	Epithelial-mesenchymal transition (EMT) Mesenchymal-epithelial transition (MET) Cell migration Cancer metastasis Actin cytoskeleton In vivo live imaging
Online Access:	https://doi.org/10.1186/s12964-021-00761-8

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