The role of BHLHE40 in clinical features and prognosis value of PDAC by comprehensive analysis and in vitro validation

The role of BHLHE40 in clinical features and prognosis value of PDAC by comprehensive analysis and in vitro validation

Pancreatic ductal adenocarcinoma (PDAC) is the leading cause of cancer-related mortality, primarily due to the abundance of cancer-associated fibroblasts (CAFs), depleted effector T cells, and increased tumor cell stemness; hence, there is an urgent need for efficient biomarkers with prognostic and...

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Bibliographic Details
Main Authors: Chao Liu, Jiang Du, Jianwei Zheng, Ruizhe Zhang, Jialin Zhu, Bofan Xing, Lin Dong, Qianqian Zhou, Xiaofeng Yao, Song Gao, Yu Wang, Yu Ren, Xuan Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
BHLHE40
PDAC
prognosis
risk model
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1151321/full

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