Body mass index and incidence of lung cancer in the HUNT study: using observational and Mendelian randomization approaches

Body mass index and incidence of lung cancer in the HUNT study: using observational and Mendelian randomization approaches

Abstract Background Traditional observational studies have shown an inverse association between body mass index (BMI) and lung cancer risk. Mendelian randomization (MR) analysis using genetic variants as instruments for BMI may clarify the nature of the association. Aims We studied the causal associ...

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Bibliographic Details
Main Authors: Lin Jiang, Yi-Qian Sun, Ben Michael Brumpton, Arnulf Langhammer, Yue Chen, Xiao-Mei Mai
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Cancer
Subjects:
Body mass index
Lung cancer incidence
Multivariable Mendelian randomization
Obesity
Prospective cohort
The HUNT Study
Online Access:https://doi.org/10.1186/s12885-022-10215-0

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