Development and validation of a differentiation-related signature based on single-cell RNA sequencing data of immune cells in spinal cord injury

Development and validation of a differentiation-related signature based on single-cell RNA sequencing data of immune cells in spinal cord injury

Background: After spinal cord injury (SCI), the native immune surveillance function of the central nervous system is activated, resulting in a substantial infiltration of immune cells into the affected tissue. While numerous studies have explored the transcriptome data following SCI and revealed cer...

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Bibliographic Details
Main Authors: Jun Shang, Chao Ma, Han Ding, Guangjin Gu, Jianping Zhang, Min Wang, Ke Fang, Zhijian Wei, Shiqing Feng
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Heliyon
Subjects:
Spinal cord injury
Single cell trajectory analysis
Immune infiltration
Molecular subtypes
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023070615

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