Erythropoietin Receptor Antagonist Suppressed Ectopic Hemoglobin Synthesis in Xenografts of HeLa Cells to Promote Their Destruction.

Erythropoietin Receptor Antagonist Suppressed Ectopic Hemoglobin Synthesis in Xenografts of HeLa Cells to Promote Their Destruction.

The aim of this study is to explore a cause-oriented therapy for patients with uterine cervical cancer that expresses erythropoietin (Epo) and its receptor (EpoR). Epo, by binding to EpoR, stimulates the proliferation and differentiation of erythroid progenitor cells into hemoglobin-containing red b...

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Bibliographic Details
Main Authors: Yoshiko Yasuda, Mitsugu Fujita, Eiji Koike, Koshiro Obata, Mitsuru Shiota, Yasushi Kotani, Terunaga Musha, Sachiyo Tsuji-Kawahara, Takao Satou, Seiji Masuda, Junko Okano, Harufumi Yamasaki, Katsumi Okumoto, Tadao Uesugi, Shinichi Nakao, Hiroshi Hoshiai, Masaki Mandai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4398449?pdf=render

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