A protocol to detect neurodegeneration in Drosophila melanogaster whole-brain mounts using advanced microscopy

A protocol to detect neurodegeneration in Drosophila melanogaster whole-brain mounts using advanced microscopy

Summary: Drosophila melanogaster is an excellent model organism to study neurodegeneration. Assessing evident neurodegeneration within the fly brain involves the laborious preparation of thin-sectioned H&E-stained heads to visualize brain vacuole degeneration. Here, we present an advanced micros...

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Bibliographic Details
Main Authors: Joseph A. Behnke, Changtian Ye, Kenneth H. Moberg, James Q. Zheng
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:STAR Protocols
Subjects:
Microscopy
Model Organisms
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721003968

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