Capture of endogenous lipids in peptidiscs and effect on protein stability and activity

Capture of endogenous lipids in peptidiscs and effect on protein stability and activity

Summary: Compared to protein–protein and protein–nucleic acid interactions, our knowledge of protein-lipid interactions remains limited. This is primarily due to the inherent insolubility of membrane proteins (MPs) in aqueous solution. The traditional use of detergents to overcome the solubility bar...

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Bibliographic Details
Main Authors: Rupinder Singh Jandu, Huaxu Yu, Zhiyu Zhao, Hai Tuong Le, Sehyeon Kim, Tao Huan, Franck Duong van Hoa
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Membrane architecture
Structural biology
Protein structure aspects
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224006035

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