Quadruplex-Forming Motif Inserted into 3′UTR of <i>Ty1his3-AI</i> Retrotransposon Inhibits Retrotransposition in Yeast

Quadruplex-Forming Motif Inserted into 3′UTR of <i>Ty1his3-AI</i> Retrotransposon Inhibits Retrotransposition in Yeast

Guanine quadruplexes (G4s) serve as regulators of replication, recombination and gene expression. G4 motifs have been recently identified in LTR retrotransposons, but their role in the retrotransposon life-cycle is yet to be understood. Therefore, we inserted G4s into the 3′UTR of <i>Ty1his3-A...

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Bibliographic Details
Main Authors: Viktor Tokan, Jose Luis Rodriguez Lorenzo, Pavel Jedlicka, Iva Kejnovska, Roman Hobza, Eduard Kejnovsky
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biology
Subjects:
<i>Ty1</i> LTR retrotransposon
G-quadruplex
retrotransposition
N-methyl mesoporphyrin (NMM)
Pif1 helicase
yeast
Online Access:https://www.mdpi.com/2079-7737/10/4/347

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