Oxidative stress decreases functional airway mannose binding lectin in COPD.

Oxidative stress decreases functional airway mannose binding lectin in COPD.

We have previously established that a defect in the ability of alveolar macrophages (AM) to phagocytose apoptotic cells (efferocytosis) and pathogens is a potential therapeutic target in COPD. We further showed that levels of mannose binding lectin (MBL; required for effective macrophage phagocytic...

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Bibliographic Details
Main Authors: Hai B Tran, Jessica Ahern, Greg Hodge, Phillip Holt, Melinda M Dean, Paul N Reynolds, Sandra Hodge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4047017?pdf=render

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