Diagnosis and treatment of patients with nonacid gastroesophageal reflux-induced chronic cough
Gastroesophageal reflux (GER) is one of the most common causes of chronic cough, and chronic cough due to GER represents a subtype of GER-related diseases. Gastroesophageal reflux-induced chronic cough (GERC) can be divided into two subgroups based on the pH of the GER. Nonacid GERC is less common t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Journal of Research in Medical Sciences |
| Subjects: | |
| Online Access: | http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2015;volume=20;issue=9;spage=885;epage=892;aulast=Xu |
| _version_ | 1819230827033133056 |
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| author | Xianghuai Xu Li Yu Qiang Chen Hanjing Lv Zhongmin Qiu |
| author_facet | Xianghuai Xu Li Yu Qiang Chen Hanjing Lv Zhongmin Qiu |
| author_sort | Xianghuai Xu |
| collection | DOAJ |
| description | Gastroesophageal reflux (GER) is one of the most common causes of chronic cough, and chronic cough due to GER represents a subtype of GER-related diseases. Gastroesophageal reflux-induced chronic cough (GERC) can be divided into two subgroups based on the pH of the GER. Nonacid GERC is less common than acid GERC, and its diagnosis and treatment strategy have not been standardized. However, nonacid GERC usually presents with its unique set of characteristics and features upon diagnosis and treatment in the clinic. Although the underlying molecular mechanism of nonacid GERC is not fully understood, it is considered to be associated with reflux theory, reflex theory and airway hypersensitivity. Multi-channel intraluminal impedance combined with pH monitoring is a promising new technique that can detect both acid and nonacid reflux, and our findings as well as those of others have shown its usefulness in diagnosing nonacid GERC. Development of new diagnostic techniques has led to an increased rate of nonacid GERC diagnosis. We summarize our experience in the diagnosis and treatment of nonacid GERC and provide a guide for future therapeutic approaches. |
| first_indexed | 2024-12-23T11:35:15Z |
| format | Article |
| id | doaj.art-7decc52cc7b84d75a2cfad0c821c7d50 |
| institution | Directory Open Access Journal |
| issn | 1735-1995 1735-7136 |
| language | English |
| last_indexed | 2024-12-23T11:35:15Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Research in Medical Sciences |
| spelling | doaj.art-7decc52cc7b84d75a2cfad0c821c7d502022-12-21T17:48:40ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362015-01-0120988589210.4103/1735-1995.170625Diagnosis and treatment of patients with nonacid gastroesophageal reflux-induced chronic coughXianghuai XuLi YuQiang ChenHanjing LvZhongmin QiuGastroesophageal reflux (GER) is one of the most common causes of chronic cough, and chronic cough due to GER represents a subtype of GER-related diseases. Gastroesophageal reflux-induced chronic cough (GERC) can be divided into two subgroups based on the pH of the GER. Nonacid GERC is less common than acid GERC, and its diagnosis and treatment strategy have not been standardized. However, nonacid GERC usually presents with its unique set of characteristics and features upon diagnosis and treatment in the clinic. Although the underlying molecular mechanism of nonacid GERC is not fully understood, it is considered to be associated with reflux theory, reflex theory and airway hypersensitivity. Multi-channel intraluminal impedance combined with pH monitoring is a promising new technique that can detect both acid and nonacid reflux, and our findings as well as those of others have shown its usefulness in diagnosing nonacid GERC. Development of new diagnostic techniques has led to an increased rate of nonacid GERC diagnosis. We summarize our experience in the diagnosis and treatment of nonacid GERC and provide a guide for future therapeutic approaches.http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2015;volume=20;issue=9;spage=885;epage=892;aulast=XuChronic coughmulti-channel intraluminal impedance combined with pH monitoringnonacid gastroesophageal reflux |
| spellingShingle | Xianghuai Xu Li Yu Qiang Chen Hanjing Lv Zhongmin Qiu Diagnosis and treatment of patients with nonacid gastroesophageal reflux-induced chronic cough Journal of Research in Medical Sciences Chronic cough multi-channel intraluminal impedance combined with pH monitoring nonacid gastroesophageal reflux |
| title | Diagnosis and treatment of patients with nonacid gastroesophageal reflux-induced chronic cough |
| title_full | Diagnosis and treatment of patients with nonacid gastroesophageal reflux-induced chronic cough |
| title_fullStr | Diagnosis and treatment of patients with nonacid gastroesophageal reflux-induced chronic cough |
| title_full_unstemmed | Diagnosis and treatment of patients with nonacid gastroesophageal reflux-induced chronic cough |
| title_short | Diagnosis and treatment of patients with nonacid gastroesophageal reflux-induced chronic cough |
| title_sort | diagnosis and treatment of patients with nonacid gastroesophageal reflux induced chronic cough |
| topic | Chronic cough multi-channel intraluminal impedance combined with pH monitoring nonacid gastroesophageal reflux |
| url | http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2015;volume=20;issue=9;spage=885;epage=892;aulast=Xu |
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