Fibroblast Growth Factor-1 Induced Promatrilysin Expression Through the Activation of Extracellular-regulated Kinases and STAT3

Fibroblast Growth Factor-1 Induced Promatrilysin Expression Through the Activation of Extracellular-regulated Kinases and STAT3

The MMP, matrilysin. (20MMP-7), has been shown to be overexpressed in prostate cancer cells and to increase prostate cancer cell invasion. Prostate stromal fibroblasts secrete factor(s), including fibroblast growth factor-1. (20FGF-1) that induces promatrilysin expression in LNCaP cells. In the pres...

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Bibliographic Details
Main Authors: Thirupandiyur S. Udayakumar, Mimi Suzanne Stratton, Raymond B. Nagle, George Timothy Bowden
Format: Article
Language:English
Published: Elsevier 2002-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
matrilysin
prostate
STAT3
FGF-1
LNCaP
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558602800483

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