Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
How factors involved in homologous recombination interact and function is a matter of interest. Here the authors use super-resolution imaging to describe the spatiotemporal dynamics of proteins associated with homologous recombination DNA repair in response to replication stress.
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2018-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-06435-3 |
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author | Donna R. Whelan Wei Ting C. Lee Yandong Yin Dylan M. Ofri Keria Bermudez-Hernandez Sarah Keegan David Fenyo Eli Rothenberg |
author_facet | Donna R. Whelan Wei Ting C. Lee Yandong Yin Dylan M. Ofri Keria Bermudez-Hernandez Sarah Keegan David Fenyo Eli Rothenberg |
author_sort | Donna R. Whelan |
collection | DOAJ |
description | How factors involved in homologous recombination interact and function is a matter of interest. Here the authors use super-resolution imaging to describe the spatiotemporal dynamics of proteins associated with homologous recombination DNA repair in response to replication stress. |
first_indexed | 2024-12-22T08:49:19Z |
format | Article |
id | doaj.art-7dede67c47fa41e5b8e6f07d588a1c84 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-22T08:49:19Z |
publishDate | 2018-09-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-7dede67c47fa41e5b8e6f07d588a1c842022-12-21T18:32:00ZengNature PortfolioNature Communications2041-17232018-09-019111510.1038/s41467-018-06435-3Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forksDonna R. Whelan0Wei Ting C. Lee1Yandong Yin2Dylan M. Ofri3Keria Bermudez-Hernandez4Sarah Keegan5David Fenyo6Eli Rothenberg7Department of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineHow factors involved in homologous recombination interact and function is a matter of interest. Here the authors use super-resolution imaging to describe the spatiotemporal dynamics of proteins associated with homologous recombination DNA repair in response to replication stress.https://doi.org/10.1038/s41467-018-06435-3 |
spellingShingle | Donna R. Whelan Wei Ting C. Lee Yandong Yin Dylan M. Ofri Keria Bermudez-Hernandez Sarah Keegan David Fenyo Eli Rothenberg Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks Nature Communications |
title | Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks |
title_full | Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks |
title_fullStr | Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks |
title_full_unstemmed | Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks |
title_short | Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks |
title_sort | spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks |
url | https://doi.org/10.1038/s41467-018-06435-3 |
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