Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks

How factors involved in homologous recombination interact and function is a matter of interest. Here the authors use super-resolution imaging to describe the spatiotemporal dynamics of proteins associated with homologous recombination DNA repair in response to replication stress.

Bibliographic Details
Main Authors: Donna R. Whelan, Wei Ting C. Lee, Yandong Yin, Dylan M. Ofri, Keria Bermudez-Hernandez, Sarah Keegan, David Fenyo, Eli Rothenberg
Format: Article
Language:English
Published: Nature Portfolio 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06435-3
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author Donna R. Whelan
Wei Ting C. Lee
Yandong Yin
Dylan M. Ofri
Keria Bermudez-Hernandez
Sarah Keegan
David Fenyo
Eli Rothenberg
author_facet Donna R. Whelan
Wei Ting C. Lee
Yandong Yin
Dylan M. Ofri
Keria Bermudez-Hernandez
Sarah Keegan
David Fenyo
Eli Rothenberg
author_sort Donna R. Whelan
collection DOAJ
description How factors involved in homologous recombination interact and function is a matter of interest. Here the authors use super-resolution imaging to describe the spatiotemporal dynamics of proteins associated with homologous recombination DNA repair in response to replication stress.
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spelling doaj.art-7dede67c47fa41e5b8e6f07d588a1c842022-12-21T18:32:00ZengNature PortfolioNature Communications2041-17232018-09-019111510.1038/s41467-018-06435-3Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forksDonna R. Whelan0Wei Ting C. Lee1Yandong Yin2Dylan M. Ofri3Keria Bermudez-Hernandez4Sarah Keegan5David Fenyo6Eli Rothenberg7Department of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineHow factors involved in homologous recombination interact and function is a matter of interest. Here the authors use super-resolution imaging to describe the spatiotemporal dynamics of proteins associated with homologous recombination DNA repair in response to replication stress.https://doi.org/10.1038/s41467-018-06435-3
spellingShingle Donna R. Whelan
Wei Ting C. Lee
Yandong Yin
Dylan M. Ofri
Keria Bermudez-Hernandez
Sarah Keegan
David Fenyo
Eli Rothenberg
Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
Nature Communications
title Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
title_full Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
title_fullStr Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
title_full_unstemmed Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
title_short Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
title_sort spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
url https://doi.org/10.1038/s41467-018-06435-3
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