Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis
Objective: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE). Methods: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnan...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-07-01
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| Series: | Hypertension in Pregnancy |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641955.2021.1921792 |
| _version_ | 1797681523095240704 |
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| author | Ahmed Arafa Xiaowen Wang Jia-Yi Dong Ehab S Eshak |
| author_facet | Ahmed Arafa Xiaowen Wang Jia-Yi Dong Ehab S Eshak |
| author_sort | Ahmed Arafa |
| collection | DOAJ |
| description | Objective: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE). Methods: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The I2 measured heterogeneity between studies. Results: Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI: 0.89, 1.09; I2 = 0.00%). Conclusion: MS is not associated with PE. |
| first_indexed | 2024-03-11T23:46:03Z |
| format | Article |
| id | doaj.art-7def72b51fa04990b3df2e893b79e28d |
| institution | Directory Open Access Journal |
| issn | 1064-1955 1525-6065 |
| language | English |
| last_indexed | 2024-03-11T23:46:03Z |
| publishDate | 2021-07-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Hypertension in Pregnancy |
| spelling | doaj.art-7def72b51fa04990b3df2e893b79e28d2023-09-19T09:24:44ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652021-07-0140318018510.1080/10641955.2021.19217921921792Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysisAhmed Arafa0Xiaowen Wang1Jia-Yi Dong2Ehab S Eshak3Osaka University Graduate School of MedicineOsaka University Graduate School of MedicineOsaka University Graduate School of MedicineOsaka University Graduate School of MedicineObjective: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE). Methods: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The I2 measured heterogeneity between studies. Results: Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI: 0.89, 1.09; I2 = 0.00%). Conclusion: MS is not associated with PE.http://dx.doi.org/10.1080/10641955.2021.1921792meta-analysismultiple sclerosispreeclampsiasystematic review |
| spellingShingle | Ahmed Arafa Xiaowen Wang Jia-Yi Dong Ehab S Eshak Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis Hypertension in Pregnancy meta-analysis multiple sclerosis preeclampsia systematic review |
| title | Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis |
| title_full | Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis |
| title_fullStr | Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis |
| title_full_unstemmed | Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis |
| title_short | Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis |
| title_sort | does multiple sclerosis increase the risk of preeclampsia a systematic review and meta analysis |
| topic | meta-analysis multiple sclerosis preeclampsia systematic review |
| url | http://dx.doi.org/10.1080/10641955.2021.1921792 |
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