Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis

Objective: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE). Methods: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnan...

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Những tác giả chính: Ahmed Arafa, Xiaowen Wang, Jia-Yi Dong, Ehab S Eshak
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Taylor & Francis Group 2021-07-01
Loạt:Hypertension in Pregnancy
Những chủ đề:
Truy cập trực tuyến:http://dx.doi.org/10.1080/10641955.2021.1921792
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author Ahmed Arafa
Xiaowen Wang
Jia-Yi Dong
Ehab S Eshak
author_facet Ahmed Arafa
Xiaowen Wang
Jia-Yi Dong
Ehab S Eshak
author_sort Ahmed Arafa
collection DOAJ
description Objective: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE). Methods: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The I2 measured heterogeneity between studies. Results: Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI: 0.89, 1.09; I2 = 0.00%). Conclusion: MS is not associated with PE.
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spelling doaj.art-7def72b51fa04990b3df2e893b79e28d2023-09-19T09:24:44ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652021-07-0140318018510.1080/10641955.2021.19217921921792Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysisAhmed Arafa0Xiaowen Wang1Jia-Yi Dong2Ehab S Eshak3Osaka University Graduate School of MedicineOsaka University Graduate School of MedicineOsaka University Graduate School of MedicineOsaka University Graduate School of MedicineObjective: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE). Methods: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The I2 measured heterogeneity between studies. Results: Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI: 0.89, 1.09; I2 = 0.00%). Conclusion: MS is not associated with PE.http://dx.doi.org/10.1080/10641955.2021.1921792meta-analysismultiple sclerosispreeclampsiasystematic review
spellingShingle Ahmed Arafa
Xiaowen Wang
Jia-Yi Dong
Ehab S Eshak
Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis
Hypertension in Pregnancy
meta-analysis
multiple sclerosis
preeclampsia
systematic review
title Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis
title_full Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis
title_fullStr Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis
title_full_unstemmed Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis
title_short Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis
title_sort does multiple sclerosis increase the risk of preeclampsia a systematic review and meta analysis
topic meta-analysis
multiple sclerosis
preeclampsia
systematic review
url http://dx.doi.org/10.1080/10641955.2021.1921792
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AT ehabseshak doesmultiplesclerosisincreasetheriskofpreeclampsiaasystematicreviewandmetaanalysis