A bone fide atypical fibroxanthoma of penis

Malignant mesenchymal tumors of the penis are very rare and they have vascular origin. We present a case of a 71-year-old man with a painless nodule of 2.0 cm in diameter located in the penile foreskin. There was no history of urinary or sexually transmitted disease. An excisional biopsy revealed a...

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Main Authors: Roberto Cuomo, Maria Addesso, Roberto Altieri, Antonio D′Antonio
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Urology Annals
Subjects:
Online Access:http://www.urologyannals.com/article.asp?issn=0974-7796;year=2014;volume=6;issue=4;spage=381;epage=383;aulast=Cuomo
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author Roberto Cuomo
Maria Addesso
Roberto Altieri
Antonio D′Antonio
author_facet Roberto Cuomo
Maria Addesso
Roberto Altieri
Antonio D′Antonio
author_sort Roberto Cuomo
collection DOAJ
description Malignant mesenchymal tumors of the penis are very rare and they have vascular origin. We present a case of a 71-year-old man with a painless nodule of 2.0 cm in diameter located in the penile foreskin. There was no history of urinary or sexually transmitted disease. An excisional biopsy revealed a markedly pleomorphic sarcoma resembling atypical fibroxanthoma (AFX) associated with a squamous cell carcinoma in situ. The patient refused a wide re-excision and was free of disease after 36 months. Because the different therapeutic management and prognosis, differential diagnosis should be made with sarcomatoid squamous cell carcinoma and melanoma: A diagnosis of AFX or malignant fibrous histiocytoma may be considered only after the complete exclusion of these two entities.
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spelling doaj.art-7df02ca593c440e49188d0fea09df1bf2022-12-22T01:29:50ZengWolters Kluwer Medknow PublicationsUrology Annals0974-77960974-78342014-01-016438138310.4103/0974-7796.141009A bone fide atypical fibroxanthoma of penisRoberto CuomoMaria AddessoRoberto AltieriAntonio D′AntonioMalignant mesenchymal tumors of the penis are very rare and they have vascular origin. We present a case of a 71-year-old man with a painless nodule of 2.0 cm in diameter located in the penile foreskin. There was no history of urinary or sexually transmitted disease. An excisional biopsy revealed a markedly pleomorphic sarcoma resembling atypical fibroxanthoma (AFX) associated with a squamous cell carcinoma in situ. The patient refused a wide re-excision and was free of disease after 36 months. Because the different therapeutic management and prognosis, differential diagnosis should be made with sarcomatoid squamous cell carcinoma and melanoma: A diagnosis of AFX or malignant fibrous histiocytoma may be considered only after the complete exclusion of these two entities.http://www.urologyannals.com/article.asp?issn=0974-7796;year=2014;volume=6;issue=4;spage=381;epage=383;aulast=CuomoAtypical fibroxanthomaCD10differential diagnosispenis
spellingShingle Roberto Cuomo
Maria Addesso
Roberto Altieri
Antonio D′Antonio
A bone fide atypical fibroxanthoma of penis
Urology Annals
Atypical fibroxanthoma
CD10
differential diagnosis
penis
title A bone fide atypical fibroxanthoma of penis
title_full A bone fide atypical fibroxanthoma of penis
title_fullStr A bone fide atypical fibroxanthoma of penis
title_full_unstemmed A bone fide atypical fibroxanthoma of penis
title_short A bone fide atypical fibroxanthoma of penis
title_sort bone fide atypical fibroxanthoma of penis
topic Atypical fibroxanthoma
CD10
differential diagnosis
penis
url http://www.urologyannals.com/article.asp?issn=0974-7796;year=2014;volume=6;issue=4;spage=381;epage=383;aulast=Cuomo
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