Autophagy: A Potential Therapeutic Target for Reversing Sepsis-Induced Immunosuppression

Autophagy: A Potential Therapeutic Target for Reversing Sepsis-Induced Immunosuppression

Sepsis remains the leading cause of mortality in intensive care units and an intractable condition due to uncontrolled inflammation together with immune suppression. Dysfunction of immune cells is considered as a major cause for poor outcome of septic patients but with little specific treatments. Cu...

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Bibliographic Details
Main Authors: Chao Ren, Hui Zhang, Tian-tian Wu, Yong-ming Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
sepsis
immunosuppression
autophagy
apoptosis
treatment
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01832/full

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