Evaluation of the hemostatic effect of 25% red mangrove gel in acute hemorrhage
Introduction: In traditional medicine, hemostatic effects are attributed to parts of the red mangrove plant (Rhizophora mangle). Objective: To evaluate the hemostatic effect of 25% red mangrove gel on acute hemorrhage. Methods: A study was carried out in an animal model with 5 groups of albino ra...
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| Format: | Article |
| Language: | Spanish |
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ECIMED
2023-06-01
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| Series: | Revista Cubana de Medicina Militar |
| Subjects: | |
| Online Access: | https://revmedmilitar.sld.cu/index.php/mil/article/view/2283 |
| _version_ | 1797802316928122880 |
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| author | Idelsis Esquivel Moynelo Maritania Vizcaino Cesar Gastón García Simón Regla Maité Casanova Orta Roberto Medina López |
| author_facet | Idelsis Esquivel Moynelo Maritania Vizcaino Cesar Gastón García Simón Regla Maité Casanova Orta Roberto Medina López |
| author_sort | Idelsis Esquivel Moynelo |
| collection | DOAJ |
| description | Introduction: In traditional medicine, hemostatic effects are attributed to parts of the red mangrove plant (Rhizophora mangle).
Objective: To evaluate the hemostatic effect of 25% red mangrove gel on acute hemorrhage.
Methods: A study was carried out in an animal model with 5 groups of albino rats; group I (warfarin), II (phytomenadione), III (0.9% sodium chloride), IV (untreated control) and V (25% red mangrove gel). One limb amputation was produced and the bleeding time (in min) and the amount of bleeding (in g) were measured. A mean comparison analysis was performed with the results of the measurements.
Results: For bleeding time, the means and standard deviations were as follows: Group I (3.12 ± 0.35), group II (1.25 ± 0.30), group III (2.94 ± 0.42); group IV (2.10 ± 0.36) and group V (0.71 ± 0.10). For the amount of bleeding, the means and standard deviations were: Group I (2.97 ± 0.20), group II (1.15 ± 0.38), group III (2.36 ± 0.30), group IV (2.90 ± 0.92) and group V (1.16 ± 0.36). For both variables there were statistically significant differences of groups II and V (p< 0.05) with the other groups and none between group II and IV.
Conclusions: The 25% red mangrove gel presents hemostatic effect similar to phytomenadione, according to the duration and amount of bleeding. |
| first_indexed | 2024-03-13T05:03:51Z |
| format | Article |
| id | doaj.art-7dfdb2ae79534130a1591f032c3353d9 |
| institution | Directory Open Access Journal |
| issn | 1561-3046 |
| language | Spanish |
| last_indexed | 2024-03-13T05:03:51Z |
| publishDate | 2023-06-01 |
| publisher | ECIMED |
| record_format | Article |
| series | Revista Cubana de Medicina Militar |
| spelling | doaj.art-7dfdb2ae79534130a1591f032c3353d92023-06-17T04:25:57ZspaECIMEDRevista Cubana de Medicina Militar1561-30462023-06-01522e02302283e02302283780Evaluation of the hemostatic effect of 25% red mangrove gel in acute hemorrhageIdelsis Esquivel Moynelo0Maritania Vizcaino Cesar1Gastón García Simón2Regla Maité Casanova Orta3Roberto Medina López4Hospital Militar Central “Dr. Luís Díaz Soto”. Departamento de Investigaciones Médico Militares. La Habana, Cuba.Hospital Militar Central “Dr. Luís Díaz Soto”. Departamento de Investigaciones Médico Militares. La Habana, Cuba.Universidad de la Habana. Instituto de Farmacia y Alimentos. Centro de Estudios para las Investigaciones y Evaluaciones Biológicas. La Habana, CubaUniversidad de la Habana. Instituto de Farmacia y Alimentos. Centro de Estudios para las Investigaciones y Evaluaciones Biológicas. La Habana, CubaUniversidad de la Habana. Instituto de Farmacia y Alimentos. Centro de Estudios para las Investigaciones y Evaluaciones Biológicas. La Habana, CubaIntroduction: In traditional medicine, hemostatic effects are attributed to parts of the red mangrove plant (Rhizophora mangle). Objective: To evaluate the hemostatic effect of 25% red mangrove gel on acute hemorrhage. Methods: A study was carried out in an animal model with 5 groups of albino rats; group I (warfarin), II (phytomenadione), III (0.9% sodium chloride), IV (untreated control) and V (25% red mangrove gel). One limb amputation was produced and the bleeding time (in min) and the amount of bleeding (in g) were measured. A mean comparison analysis was performed with the results of the measurements. Results: For bleeding time, the means and standard deviations were as follows: Group I (3.12 ± 0.35), group II (1.25 ± 0.30), group III (2.94 ± 0.42); group IV (2.10 ± 0.36) and group V (0.71 ± 0.10). For the amount of bleeding, the means and standard deviations were: Group I (2.97 ± 0.20), group II (1.15 ± 0.38), group III (2.36 ± 0.30), group IV (2.90 ± 0.92) and group V (1.16 ± 0.36). For both variables there were statistically significant differences of groups II and V (p< 0.05) with the other groups and none between group II and IV. Conclusions: The 25% red mangrove gel presents hemostatic effect similar to phytomenadione, according to the duration and amount of bleeding.https://revmedmilitar.sld.cu/index.php/mil/article/view/2283animaleshemorragiahemostasishemostáticosratasrhizophoraceae. |
| spellingShingle | Idelsis Esquivel Moynelo Maritania Vizcaino Cesar Gastón García Simón Regla Maité Casanova Orta Roberto Medina López Evaluation of the hemostatic effect of 25% red mangrove gel in acute hemorrhage Revista Cubana de Medicina Militar animales hemorragia hemostasis hemostáticos ratas rhizophoraceae. |
| title | Evaluation of the hemostatic effect of 25% red mangrove gel in acute hemorrhage |
| title_full | Evaluation of the hemostatic effect of 25% red mangrove gel in acute hemorrhage |
| title_fullStr | Evaluation of the hemostatic effect of 25% red mangrove gel in acute hemorrhage |
| title_full_unstemmed | Evaluation of the hemostatic effect of 25% red mangrove gel in acute hemorrhage |
| title_short | Evaluation of the hemostatic effect of 25% red mangrove gel in acute hemorrhage |
| title_sort | evaluation of the hemostatic effect of 25 red mangrove gel in acute hemorrhage |
| topic | animales hemorragia hemostasis hemostáticos ratas rhizophoraceae. |
| url | https://revmedmilitar.sld.cu/index.php/mil/article/view/2283 |
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