An Elaboration on Sample Size Planning for Performing a One-Sample Sensitivity and Specificity Analysis by Basing on Calculations on a Specified 95% Confidence Interval Width
Sample size calculation based on a specified width of 95% confidence interval will offer researchers the freedom to set the level of accuracy of the statistics that they aim to achieve for a particular study. This paper provides a description of the general conceptual context for performing sensitiv...
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Format: | Article |
Language: | English |
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MDPI AG
2023-04-01
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Series: | Diagnostics |
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Online Access: | https://www.mdpi.com/2075-4418/13/8/1390 |
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author | Mohamad Adam Bujang |
author_facet | Mohamad Adam Bujang |
author_sort | Mohamad Adam Bujang |
collection | DOAJ |
description | Sample size calculation based on a specified width of 95% confidence interval will offer researchers the freedom to set the level of accuracy of the statistics that they aim to achieve for a particular study. This paper provides a description of the general conceptual context for performing sensitivity and specificity analysis. Subsequently, sample size tables for sensitivity and specificity analysis based on a specified 95% confidence interval width is then provided. Such recommendations for sample size planning are provided based on two different scenarios: one for a diagnostic purpose and another for a screening purpose. Further discussion on all the other relevant considerations for the determination of a minimum sample size requirement and on how to draft the sample size statement for performing sensitivity and specificity analysis are also provided. |
first_indexed | 2024-03-11T05:06:09Z |
format | Article |
id | doaj.art-7e00a5f1584e4767880b4bfc14fc4709 |
institution | Directory Open Access Journal |
issn | 2075-4418 |
language | English |
last_indexed | 2024-03-11T05:06:09Z |
publishDate | 2023-04-01 |
publisher | MDPI AG |
record_format | Article |
series | Diagnostics |
spelling | doaj.art-7e00a5f1584e4767880b4bfc14fc47092023-11-17T18:54:26ZengMDPI AGDiagnostics2075-44182023-04-01138139010.3390/diagnostics13081390An Elaboration on Sample Size Planning for Performing a One-Sample Sensitivity and Specificity Analysis by Basing on Calculations on a Specified 95% Confidence Interval WidthMohamad Adam Bujang0Clinical Research Centre, Sarawak General Hospital, Ministry of Health Malaysia, Kuching 93586, MalaysiaSample size calculation based on a specified width of 95% confidence interval will offer researchers the freedom to set the level of accuracy of the statistics that they aim to achieve for a particular study. This paper provides a description of the general conceptual context for performing sensitivity and specificity analysis. Subsequently, sample size tables for sensitivity and specificity analysis based on a specified 95% confidence interval width is then provided. Such recommendations for sample size planning are provided based on two different scenarios: one for a diagnostic purpose and another for a screening purpose. Further discussion on all the other relevant considerations for the determination of a minimum sample size requirement and on how to draft the sample size statement for performing sensitivity and specificity analysis are also provided.https://www.mdpi.com/2075-4418/13/8/1390confidence intervalsample sizesensitivityspecificity |
spellingShingle | Mohamad Adam Bujang An Elaboration on Sample Size Planning for Performing a One-Sample Sensitivity and Specificity Analysis by Basing on Calculations on a Specified 95% Confidence Interval Width Diagnostics confidence interval sample size sensitivity specificity |
title | An Elaboration on Sample Size Planning for Performing a One-Sample Sensitivity and Specificity Analysis by Basing on Calculations on a Specified 95% Confidence Interval Width |
title_full | An Elaboration on Sample Size Planning for Performing a One-Sample Sensitivity and Specificity Analysis by Basing on Calculations on a Specified 95% Confidence Interval Width |
title_fullStr | An Elaboration on Sample Size Planning for Performing a One-Sample Sensitivity and Specificity Analysis by Basing on Calculations on a Specified 95% Confidence Interval Width |
title_full_unstemmed | An Elaboration on Sample Size Planning for Performing a One-Sample Sensitivity and Specificity Analysis by Basing on Calculations on a Specified 95% Confidence Interval Width |
title_short | An Elaboration on Sample Size Planning for Performing a One-Sample Sensitivity and Specificity Analysis by Basing on Calculations on a Specified 95% Confidence Interval Width |
title_sort | elaboration on sample size planning for performing a one sample sensitivity and specificity analysis by basing on calculations on a specified 95 confidence interval width |
topic | confidence interval sample size sensitivity specificity |
url | https://www.mdpi.com/2075-4418/13/8/1390 |
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