Preparation and Crosslinking Capacity of Dialdoxylose
Objective: To design and synthesize dialdoxylose, a glutaraldehyde analogue which is expected to have a low toxicity, and to characterize its performance in crosslinking chitosan in 1% acetic acid solution. Methods: Dialdoxylose was obtained by sodium periodate oxidation and deprotection of monoacet...
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| Format: | Article |
| Language: | English |
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China Food Publishing Company
2023-10-01
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| Series: | Shipin Kexue |
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| Online Access: | https://www.spkx.net.cn/fileup/1002-6630/PDF/2023-44-20-009.pdf |
| _version_ | 1797435859751927808 |
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| author | JING Shutong, LI Zhengsheng’ao, LI Han, CAO Honghua, LI Xuecong, LIU Yonghao, YU Jiaqi, WEN Jingru, SUN Xun |
| author_facet | JING Shutong, LI Zhengsheng’ao, LI Han, CAO Honghua, LI Xuecong, LIU Yonghao, YU Jiaqi, WEN Jingru, SUN Xun |
| author_sort | JING Shutong, LI Zhengsheng’ao, LI Han, CAO Honghua, LI Xuecong, LIU Yonghao, YU Jiaqi, WEN Jingru, SUN Xun |
| collection | DOAJ |
| description | Objective: To design and synthesize dialdoxylose, a glutaraldehyde analogue which is expected to have a low toxicity, and to characterize its performance in crosslinking chitosan in 1% acetic acid solution. Methods: Dialdoxylose was obtained by sodium periodate oxidation and deprotection of monoacetone glucose and used to form crosslinked chitosan gels. The gel strength, fluid properties, water activity and thermal stability of chitosan gels were analyzed by texture profile analysis (TPA), low field-nuclear magnetic resonance (NMR) spectroscopy and differential scanning calorimetry (DSC). Results: It was found that dialdoxylose exhibited two structures in water, (α,β) and (β,β), with a ratio of 44.4:65.6. The hardness, viscosity and water-holding capacity of the chitosan gel crosslinked with 0.002 g/mL dialdoxylose were highest. Conclusion: Dialdoxylose has an obvious crosslinking effect on chitosan, which is greatly affected by its concentration. The results of this study are of theoretical guiding significance for the development of new low-toxicity small-molecule crosslinking agents. |
| first_indexed | 2024-03-09T10:54:22Z |
| format | Article |
| id | doaj.art-7e02b974ce294ce8a959063fa4a1ddb3 |
| institution | Directory Open Access Journal |
| issn | 1002-6630 |
| language | English |
| last_indexed | 2024-03-09T10:54:22Z |
| publishDate | 2023-10-01 |
| publisher | China Food Publishing Company |
| record_format | Article |
| series | Shipin Kexue |
| spelling | doaj.art-7e02b974ce294ce8a959063fa4a1ddb32023-12-01T03:19:24ZengChina Food Publishing CompanyShipin Kexue1002-66302023-10-014420717810.7506/spkx1002-6630-20221203-032Preparation and Crosslinking Capacity of DialdoxyloseJING Shutong, LI Zhengsheng’ao, LI Han, CAO Honghua, LI Xuecong, LIU Yonghao, YU Jiaqi, WEN Jingru, SUN Xun0(1. College of Food Science and Engineering, Ocean University of China, Qingdao 266000, China; 2. Institute of Frontier Science and Technology, Xi’an Jiaotong University, Xi’an 710054, China)Objective: To design and synthesize dialdoxylose, a glutaraldehyde analogue which is expected to have a low toxicity, and to characterize its performance in crosslinking chitosan in 1% acetic acid solution. Methods: Dialdoxylose was obtained by sodium periodate oxidation and deprotection of monoacetone glucose and used to form crosslinked chitosan gels. The gel strength, fluid properties, water activity and thermal stability of chitosan gels were analyzed by texture profile analysis (TPA), low field-nuclear magnetic resonance (NMR) spectroscopy and differential scanning calorimetry (DSC). Results: It was found that dialdoxylose exhibited two structures in water, (α,β) and (β,β), with a ratio of 44.4:65.6. The hardness, viscosity and water-holding capacity of the chitosan gel crosslinked with 0.002 g/mL dialdoxylose were highest. Conclusion: Dialdoxylose has an obvious crosslinking effect on chitosan, which is greatly affected by its concentration. The results of this study are of theoretical guiding significance for the development of new low-toxicity small-molecule crosslinking agents.https://www.spkx.net.cn/fileup/1002-6630/PDF/2023-44-20-009.pdfcrosslinking; chitosan; gel; dialdoxylose |
| spellingShingle | JING Shutong, LI Zhengsheng’ao, LI Han, CAO Honghua, LI Xuecong, LIU Yonghao, YU Jiaqi, WEN Jingru, SUN Xun Preparation and Crosslinking Capacity of Dialdoxylose Shipin Kexue crosslinking; chitosan; gel; dialdoxylose |
| title | Preparation and Crosslinking Capacity of Dialdoxylose |
| title_full | Preparation and Crosslinking Capacity of Dialdoxylose |
| title_fullStr | Preparation and Crosslinking Capacity of Dialdoxylose |
| title_full_unstemmed | Preparation and Crosslinking Capacity of Dialdoxylose |
| title_short | Preparation and Crosslinking Capacity of Dialdoxylose |
| title_sort | preparation and crosslinking capacity of dialdoxylose |
| topic | crosslinking; chitosan; gel; dialdoxylose |
| url | https://www.spkx.net.cn/fileup/1002-6630/PDF/2023-44-20-009.pdf |
| work_keys_str_mv | AT jingshutonglizhengshengaolihancaohonghualixuecongliuyonghaoyujiaqiwenjingrusunxun preparationandcrosslinkingcapacityofdialdoxylose |