Synthesis, Characterization and Physicochemical Properties of Biogenic Silver Nanoparticle-Encapsulated Chitosan Bionanocomposites
Green bionanocomposites have garnered considerable attention and applications in the pharmaceutical and packaging industries because of their intrinsic features, such as biocompatibility and biodegradability. The work presents a novel approach towards the combined effect of glycerol, tween 80 and si...
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MDPI AG
2022-01-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/14/3/463 |
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| author | Sreelekha Ediyilyam Mahesh M. Lalitha Bini George Sarojini Sharath Shankar Stanisław Wacławek Miroslav Černík Vinod Vellora Thekkae Padil |
| author_facet | Sreelekha Ediyilyam Mahesh M. Lalitha Bini George Sarojini Sharath Shankar Stanisław Wacławek Miroslav Černík Vinod Vellora Thekkae Padil |
| author_sort | Sreelekha Ediyilyam |
| collection | DOAJ |
| description | Green bionanocomposites have garnered considerable attention and applications in the pharmaceutical and packaging industries because of their intrinsic features, such as biocompatibility and biodegradability. The work presents a novel approach towards the combined effect of glycerol, tween 80 and silver nanoparticles (AgNPs) on the physicochemical properties of lyophilized chitosan (CH) scaffolds produced via a green synthesis method.The produced bionanocomposites were characterized with the help of Fourier transform infrared spectroscopy (FTIR) and Scanning electron microscopy (SEM). The swelling behavior, water vapor transmission rate, moisture retention capability, degradation in Hanks solution, biodegradability in soil, mechanical strength and electrochemical performance of the composites were evaluated. The addition of additives to the CH matrix alters the physicochemical and biological functioning of the matrix. Plasticized scaffolds showed an increase in swelling degree, water vapor transmission rate and degradability in Hank’s balanced solution compared to the blank chitosan scaffolds. The addition of tween 80 made the scaffolds more porous, and changes in physicochemical properties were observed. Green-synthesized AgNPs showed intensified antioxidant and antibacterial properties. Incorporating biogenic nanoparticles into the CH matrix enhances the polymer composites’ biochemical properties and increases the demand in the medical and biological sectors. These freeze-dried chitosan-AgNPs composite scaffolds had tremendous applications, especially in biomedical fields like wound dressing, tissue engineering, bone regeneration, etc. |
| first_indexed | 2024-03-09T23:16:42Z |
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| id | doaj.art-7e0a8b3adc614f7b91a494647b3ae9ed |
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| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-09T23:16:42Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-7e0a8b3adc614f7b91a494647b3ae9ed2023-11-23T17:34:14ZengMDPI AGPolymers2073-43602022-01-0114346310.3390/polym14030463Synthesis, Characterization and Physicochemical Properties of Biogenic Silver Nanoparticle-Encapsulated Chitosan BionanocompositesSreelekha Ediyilyam0Mahesh M. Lalitha1Bini George2Sarojini Sharath Shankar3Stanisław Wacławek4Miroslav Černík5Vinod Vellora Thekkae Padil6Department of Chemistry, School of Physical Sciences, Central University of Kerala, Kasaragod 671316, IndiaDepartment of Chemistry, School of Physical Sciences, Central University of Kerala, Kasaragod 671316, IndiaDepartment of Chemistry, School of Physical Sciences, Central University of Kerala, Kasaragod 671316, IndiaDepartment of Biochemistry and Molecular Biology, School of Biological Sciences, Central University of Kerala, Kasaragod 671316, IndiaInstitute for Nanomaterials, Advanced Technologies and Innovation (CXI), Technical University of Liberec (TUL), Studentská 1402/2, 461 17 Liberec, Czech RepublicInstitute for Nanomaterials, Advanced Technologies and Innovation (CXI), Technical University of Liberec (TUL), Studentská 1402/2, 461 17 Liberec, Czech RepublicInstitute for Nanomaterials, Advanced Technologies and Innovation (CXI), Technical University of Liberec (TUL), Studentská 1402/2, 461 17 Liberec, Czech RepublicGreen bionanocomposites have garnered considerable attention and applications in the pharmaceutical and packaging industries because of their intrinsic features, such as biocompatibility and biodegradability. The work presents a novel approach towards the combined effect of glycerol, tween 80 and silver nanoparticles (AgNPs) on the physicochemical properties of lyophilized chitosan (CH) scaffolds produced via a green synthesis method.The produced bionanocomposites were characterized with the help of Fourier transform infrared spectroscopy (FTIR) and Scanning electron microscopy (SEM). The swelling behavior, water vapor transmission rate, moisture retention capability, degradation in Hanks solution, biodegradability in soil, mechanical strength and electrochemical performance of the composites were evaluated. The addition of additives to the CH matrix alters the physicochemical and biological functioning of the matrix. Plasticized scaffolds showed an increase in swelling degree, water vapor transmission rate and degradability in Hank’s balanced solution compared to the blank chitosan scaffolds. The addition of tween 80 made the scaffolds more porous, and changes in physicochemical properties were observed. Green-synthesized AgNPs showed intensified antioxidant and antibacterial properties. Incorporating biogenic nanoparticles into the CH matrix enhances the polymer composites’ biochemical properties and increases the demand in the medical and biological sectors. These freeze-dried chitosan-AgNPs composite scaffolds had tremendous applications, especially in biomedical fields like wound dressing, tissue engineering, bone regeneration, etc.https://www.mdpi.com/2073-4360/14/3/463bionanocompositeschitosan scaffoldsilver nanoparticlesantioxidantantibacterialtween 80 |
| spellingShingle | Sreelekha Ediyilyam Mahesh M. Lalitha Bini George Sarojini Sharath Shankar Stanisław Wacławek Miroslav Černík Vinod Vellora Thekkae Padil Synthesis, Characterization and Physicochemical Properties of Biogenic Silver Nanoparticle-Encapsulated Chitosan Bionanocomposites Polymers bionanocomposites chitosan scaffold silver nanoparticles antioxidant antibacterial tween 80 |
| title | Synthesis, Characterization and Physicochemical Properties of Biogenic Silver Nanoparticle-Encapsulated Chitosan Bionanocomposites |
| title_full | Synthesis, Characterization and Physicochemical Properties of Biogenic Silver Nanoparticle-Encapsulated Chitosan Bionanocomposites |
| title_fullStr | Synthesis, Characterization and Physicochemical Properties of Biogenic Silver Nanoparticle-Encapsulated Chitosan Bionanocomposites |
| title_full_unstemmed | Synthesis, Characterization and Physicochemical Properties of Biogenic Silver Nanoparticle-Encapsulated Chitosan Bionanocomposites |
| title_short | Synthesis, Characterization and Physicochemical Properties of Biogenic Silver Nanoparticle-Encapsulated Chitosan Bionanocomposites |
| title_sort | synthesis characterization and physicochemical properties of biogenic silver nanoparticle encapsulated chitosan bionanocomposites |
| topic | bionanocomposites chitosan scaffold silver nanoparticles antioxidant antibacterial tween 80 |
| url | https://www.mdpi.com/2073-4360/14/3/463 |
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