Unusual case of pulmonary renal syndrome with autopsy findings
Scleroderma renal crises (SRC) is a serious complication of systemic sclerosis whose prognosis remains serious despite management with angiotensin-converting enzyme inhibitors, antihypertensives and dialysis. Pulmonary renal syndrome (PRS), characterised by diffuse alveolar hemorrhage (DAH) and SRC,...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2013;volume=56;issue=3;spage=294;epage=296;aulast=Badwal |
| _version_ | 1818217145241174016 |
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| author | Sonia Badwal Jyoti Kotwal Prem Prakash Varma |
| author_facet | Sonia Badwal Jyoti Kotwal Prem Prakash Varma |
| author_sort | Sonia Badwal |
| collection | DOAJ |
| description | Scleroderma renal crises (SRC) is a serious complication of systemic sclerosis whose prognosis remains serious despite management with angiotensin-converting enzyme inhibitors, antihypertensives and dialysis. Pulmonary renal syndrome (PRS), characterised by diffuse alveolar hemorrhage (DAH) and SRC, is rare and carries a grave prognosis. This case report discusses the clinicopathological features of a 43-year-old male presenting with severe hypertension and rapidly progressive renal failure who subsequently developed DAH and died. The clinical course, exhaustive investigative work-up and autopsy findings led to a diagnosis of diffuse systemic sclerosis with PRS subcategorized into PRS with thrombotic microangiopathy. The index case came without a prior diagnosis of systemic sclerosis, thereby posing a serious diagnostic challenge and management issues. |
| first_indexed | 2024-12-12T07:03:13Z |
| format | Article |
| id | doaj.art-7e0abbdee2204884a5c7bf009bdfd3f8 |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-12-12T07:03:13Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-7e0abbdee2204884a5c7bf009bdfd3f82022-12-22T00:33:48ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292013-01-0156329429610.4103/0377-4929.120403Unusual case of pulmonary renal syndrome with autopsy findingsSonia BadwalJyoti KotwalPrem Prakash VarmaScleroderma renal crises (SRC) is a serious complication of systemic sclerosis whose prognosis remains serious despite management with angiotensin-converting enzyme inhibitors, antihypertensives and dialysis. Pulmonary renal syndrome (PRS), characterised by diffuse alveolar hemorrhage (DAH) and SRC, is rare and carries a grave prognosis. This case report discusses the clinicopathological features of a 43-year-old male presenting with severe hypertension and rapidly progressive renal failure who subsequently developed DAH and died. The clinical course, exhaustive investigative work-up and autopsy findings led to a diagnosis of diffuse systemic sclerosis with PRS subcategorized into PRS with thrombotic microangiopathy. The index case came without a prior diagnosis of systemic sclerosis, thereby posing a serious diagnostic challenge and management issues.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2013;volume=56;issue=3;spage=294;epage=296;aulast=BadwalDiffuse alveolar hemorrhagesystemic sclerosisthrombotic microangiopathy |
| spellingShingle | Sonia Badwal Jyoti Kotwal Prem Prakash Varma Unusual case of pulmonary renal syndrome with autopsy findings Indian Journal of Pathology and Microbiology Diffuse alveolar hemorrhage systemic sclerosis thrombotic microangiopathy |
| title | Unusual case of pulmonary renal syndrome with autopsy findings |
| title_full | Unusual case of pulmonary renal syndrome with autopsy findings |
| title_fullStr | Unusual case of pulmonary renal syndrome with autopsy findings |
| title_full_unstemmed | Unusual case of pulmonary renal syndrome with autopsy findings |
| title_short | Unusual case of pulmonary renal syndrome with autopsy findings |
| title_sort | unusual case of pulmonary renal syndrome with autopsy findings |
| topic | Diffuse alveolar hemorrhage systemic sclerosis thrombotic microangiopathy |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2013;volume=56;issue=3;spage=294;epage=296;aulast=Badwal |
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