Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type
We report a rare case of localized NK/T-cell lymphoma following a mosquito bite after achieving complete response of extranodal NK/T-cell lymphoma, nasal type (ENKL). T cells and NK cells infected by Epstein-Barr virus (EBV) lead to NK/T-cell lymphoma, including ENKL. Lymphoma related to mosquito bi...
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Format: | Article |
Language: | English |
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Karger Publishers
2019-06-01
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Series: | Case Reports in Dermatology |
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Online Access: | https://www.karger.com/Article/FullText/501358 |
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author | Makoto Kondo Minoru Mizutani Keiichi Yamanaka |
author_facet | Makoto Kondo Minoru Mizutani Keiichi Yamanaka |
author_sort | Makoto Kondo |
collection | DOAJ |
description | We report a rare case of localized NK/T-cell lymphoma following a mosquito bite after achieving complete response of extranodal NK/T-cell lymphoma, nasal type (ENKL). T cells and NK cells infected by Epstein-Barr virus (EBV) lead to NK/T-cell lymphoma, including ENKL. Lymphoma related to mosquito bites usually requires a prolonged treatment course, and the disease onset of hypersensitivity begins in early childhood. In the current case, the patient had no history of hypersensitivity to mosquito bites. We speculate that the latently EBV-infected NK/T cells in the blood were reactivated by mosquito gland antigens, expanded abnormally, and accumulated at the site of the mosquito bite. |
first_indexed | 2024-04-14T07:38:33Z |
format | Article |
id | doaj.art-7e0bf0fbe43443478994104db2c77d3c |
institution | Directory Open Access Journal |
issn | 1662-6567 |
language | English |
last_indexed | 2024-04-14T07:38:33Z |
publishDate | 2019-06-01 |
publisher | Karger Publishers |
record_format | Article |
series | Case Reports in Dermatology |
spelling | doaj.art-7e0bf0fbe43443478994104db2c77d3c2022-12-22T02:05:36ZengKarger PublishersCase Reports in Dermatology1662-65672019-06-0111219419710.1159/000501358501358Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal TypeMakoto KondoMinoru MizutaniKeiichi YamanakaWe report a rare case of localized NK/T-cell lymphoma following a mosquito bite after achieving complete response of extranodal NK/T-cell lymphoma, nasal type (ENKL). T cells and NK cells infected by Epstein-Barr virus (EBV) lead to NK/T-cell lymphoma, including ENKL. Lymphoma related to mosquito bites usually requires a prolonged treatment course, and the disease onset of hypersensitivity begins in early childhood. In the current case, the patient had no history of hypersensitivity to mosquito bites. We speculate that the latently EBV-infected NK/T cells in the blood were reactivated by mosquito gland antigens, expanded abnormally, and accumulated at the site of the mosquito bite.https://www.karger.com/Article/FullText/501358Extranodal NK/T-cell lymphoma, nasal typeEpstein-Barr virus infectionMosquito biteComplete responseMalignant lymphoma |
spellingShingle | Makoto Kondo Minoru Mizutani Keiichi Yamanaka Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type Case Reports in Dermatology Extranodal NK/T-cell lymphoma, nasal type Epstein-Barr virus infection Mosquito bite Complete response Malignant lymphoma |
title | Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type |
title_full | Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type |
title_fullStr | Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type |
title_full_unstemmed | Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type |
title_short | Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type |
title_sort | mosquito bite induced localized nk t cell lymphoma relapsed in a patient with complete remission of extranodal nk t cell lymphoma nasal type |
topic | Extranodal NK/T-cell lymphoma, nasal type Epstein-Barr virus infection Mosquito bite Complete response Malignant lymphoma |
url | https://www.karger.com/Article/FullText/501358 |
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