Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type

We report a rare case of localized NK/T-cell lymphoma following a mosquito bite after achieving complete response of extranodal NK/T-cell lymphoma, nasal type (ENKL). T cells and NK cells infected by Epstein-Barr virus (EBV) lead to NK/T-cell lymphoma, including ENKL. Lymphoma related to mosquito bi...

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Main Authors: Makoto Kondo, Minoru Mizutani, Keiichi Yamanaka
Format: Article
Language:English
Published: Karger Publishers 2019-06-01
Series:Case Reports in Dermatology
Subjects:
Online Access:https://www.karger.com/Article/FullText/501358
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author Makoto Kondo
Minoru Mizutani
Keiichi Yamanaka
author_facet Makoto Kondo
Minoru Mizutani
Keiichi Yamanaka
author_sort Makoto Kondo
collection DOAJ
description We report a rare case of localized NK/T-cell lymphoma following a mosquito bite after achieving complete response of extranodal NK/T-cell lymphoma, nasal type (ENKL). T cells and NK cells infected by Epstein-Barr virus (EBV) lead to NK/T-cell lymphoma, including ENKL. Lymphoma related to mosquito bites usually requires a prolonged treatment course, and the disease onset of hypersensitivity begins in early childhood. In the current case, the patient had no history of hypersensitivity to mosquito bites. We speculate that the latently EBV-infected NK/T cells in the blood were reactivated by mosquito gland antigens, expanded abnormally, and accumulated at the site of the mosquito bite.
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spelling doaj.art-7e0bf0fbe43443478994104db2c77d3c2022-12-22T02:05:36ZengKarger PublishersCase Reports in Dermatology1662-65672019-06-0111219419710.1159/000501358501358Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal TypeMakoto KondoMinoru MizutaniKeiichi YamanakaWe report a rare case of localized NK/T-cell lymphoma following a mosquito bite after achieving complete response of extranodal NK/T-cell lymphoma, nasal type (ENKL). T cells and NK cells infected by Epstein-Barr virus (EBV) lead to NK/T-cell lymphoma, including ENKL. Lymphoma related to mosquito bites usually requires a prolonged treatment course, and the disease onset of hypersensitivity begins in early childhood. In the current case, the patient had no history of hypersensitivity to mosquito bites. We speculate that the latently EBV-infected NK/T cells in the blood were reactivated by mosquito gland antigens, expanded abnormally, and accumulated at the site of the mosquito bite.https://www.karger.com/Article/FullText/501358Extranodal NK/T-cell lymphoma, nasal typeEpstein-Barr virus infectionMosquito biteComplete responseMalignant lymphoma
spellingShingle Makoto Kondo
Minoru Mizutani
Keiichi Yamanaka
Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type
Case Reports in Dermatology
Extranodal NK/T-cell lymphoma, nasal type
Epstein-Barr virus infection
Mosquito bite
Complete response
Malignant lymphoma
title Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type
title_full Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type
title_fullStr Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type
title_full_unstemmed Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type
title_short Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type
title_sort mosquito bite induced localized nk t cell lymphoma relapsed in a patient with complete remission of extranodal nk t cell lymphoma nasal type
topic Extranodal NK/T-cell lymphoma, nasal type
Epstein-Barr virus infection
Mosquito bite
Complete response
Malignant lymphoma
url https://www.karger.com/Article/FullText/501358
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