Vulgarin, a Sesquiterpene Lactone from <i>Artemisia judaica</i>, Improves the Antidiabetic Effectiveness of Glibenclamide in Streptozotocin-Induced Diabetic Rats via Modulation of PEPCK and G6Pase Genes Expression

Vulgarin, a Sesquiterpene Lactone from <i>Artemisia judaica</i>, Improves the Antidiabetic Effectiveness of Glibenclamide in Streptozotocin-Induced Diabetic Rats via Modulation of PEPCK and G6Pase Genes Expression

The current investigation assessed the effect of the eudesmanolid, Vulgarin (VGN), obtained from <i>Artemisia judaica</i> (<i>A. judaica</i>), on the antidiabetic potential of glibenclamide (GLB) using streptozotocin (STZ) to induce diabetes. Seven groups of rats were used in...

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Bibliographic Details
Main Authors: Hassan N. Althurwi, Gamal A. Soliman, Rehab F. Abdel-Rahman, Reham M. Abd-Elsalam, Hanan A. Ogaly, Mohammed H. Alqarni, Faisal F. Albaqami, Maged S. Abdel-Kader
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
vulgarin
streptozotocin
glibenclamide
PEPCK
G6Pas
rat
Online Access:https://www.mdpi.com/1422-0067/23/24/15856

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