Evaluation of titanium-prepared platelet-rich fibrin and leucocyteplatelet-rich fibrin in the treatment of intra-bony defects: Arandomized clinical trial
Background. Various treatment modalities, such as leucocyte platelet-rich fibrin (L-PRF), bone grafts,and membranes, have been used for the restoration of lost periodontal tissues. Titanium-preparedplatelet-rich fibrin (T-PRF) has attracted attention for its proper haemocompatibility, thick fibrinme...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2020-06-01
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| Series: | Journal of Dental Research, Dental Clinics, Dental Prospects |
| Subjects: | |
| Online Access: | https://joddd.tbzmed.ac.ir/PDF/joddd-27954 |
| Summary: | Background. Various treatment modalities, such as leucocyte platelet-rich fibrin (L-PRF), bone grafts,and membranes, have been used for the restoration of lost periodontal tissues. Titanium-preparedplatelet-rich fibrin (T-PRF) has attracted attention for its proper haemocompatibility, thick fibrinmeshwork, and long resorption time. The present study aimed to evaluate the effectiveness of T-PRFand L-PRF in the management of intra-bony defects based on clinical and radiographic criteria. Methods. Twenty-six subjects with 34 intra-bony 3- walled defects were divided into two groups (n=17)and treated with T-PRF or L-PRF. Clinical and radiographic measurements were recorded at baselineand 6- , 3- and 9- month intervals and tabulated on Microsoft Excel spreadsheets. For intra- and intergroupcomparisons, paired and unpaired t-tests were performed. P<0.05 was set as statistically significant Results. Intra-group comparisons revealed statistically significant differences (P<0.05) from baseline inboth groups regarding clinical measurements. On intergroup comparison, the T-PRF group exhibited asignificantly higher defect fill compared to the L-PRF group (P<0.05). Conclusion. Within the limits of the present study, T-PRF seems to be a better alternative to L-PRF inthe treatment of intra-bony defects. |
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| ISSN: | 2008-210X 2008-2118 |