Evaluation of titanium-prepared platelet-rich fibrin and leucocyteplatelet-rich fibrin in the treatment of intra-bony defects: Arandomized clinical trial
Background. Various treatment modalities, such as leucocyte platelet-rich fibrin (L-PRF), bone grafts,and membranes, have been used for the restoration of lost periodontal tissues. Titanium-preparedplatelet-rich fibrin (T-PRF) has attracted attention for its proper haemocompatibility, thick fibrinme...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2020-06-01
|
| Series: | Journal of Dental Research, Dental Clinics, Dental Prospects |
| Subjects: | |
| Online Access: | https://joddd.tbzmed.ac.ir/PDF/joddd-27954 |
| _version_ | 1818275382085812224 |
|---|---|
| author | Shiva Shankar Gummaluri Hirak S Bhattacharya Madhusudan Astekar Shivani Cheruvu |
| author_facet | Shiva Shankar Gummaluri Hirak S Bhattacharya Madhusudan Astekar Shivani Cheruvu |
| author_sort | Shiva Shankar Gummaluri |
| collection | DOAJ |
| description | Background. Various treatment modalities, such as leucocyte platelet-rich fibrin (L-PRF), bone grafts,and membranes, have been used for the restoration of lost periodontal tissues. Titanium-preparedplatelet-rich fibrin (T-PRF) has attracted attention for its proper haemocompatibility, thick fibrinmeshwork, and long resorption time. The present study aimed to evaluate the effectiveness of T-PRFand L-PRF in the management of intra-bony defects based on clinical and radiographic criteria. Methods. Twenty-six subjects with 34 intra-bony 3- walled defects were divided into two groups (n=17)and treated with T-PRF or L-PRF. Clinical and radiographic measurements were recorded at baselineand 6- , 3- and 9- month intervals and tabulated on Microsoft Excel spreadsheets. For intra- and intergroupcomparisons, paired and unpaired t-tests were performed. P<0.05 was set as statistically significant Results. Intra-group comparisons revealed statistically significant differences (P<0.05) from baseline inboth groups regarding clinical measurements. On intergroup comparison, the T-PRF group exhibited asignificantly higher defect fill compared to the L-PRF group (P<0.05). Conclusion. Within the limits of the present study, T-PRF seems to be a better alternative to L-PRF inthe treatment of intra-bony defects. |
| first_indexed | 2024-12-12T22:28:52Z |
| format | Article |
| id | doaj.art-7e135f5133f74e1292c25300e2ba0355 |
| institution | Directory Open Access Journal |
| issn | 2008-210X 2008-2118 |
| language | English |
| last_indexed | 2024-12-12T22:28:52Z |
| publishDate | 2020-06-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Dental Research, Dental Clinics, Dental Prospects |
| spelling | doaj.art-7e135f5133f74e1292c25300e2ba03552022-12-22T00:09:41ZengTabriz University of Medical SciencesJournal of Dental Research, Dental Clinics, Dental Prospects2008-210X2008-21182020-06-01142839110.34172/joddd.2020.020joddd-27954Evaluation of titanium-prepared platelet-rich fibrin and leucocyteplatelet-rich fibrin in the treatment of intra-bony defects: Arandomized clinical trialShiva Shankar Gummaluri0Hirak S Bhattacharya1Madhusudan Astekar2Shivani Cheruvu3Department of Periodontology and Implantology, Institute of Dental Sciences, Bareilly, Uttar Pradesh, IndiaDepartment of Oral Pathology and Microbiology, Institute of Dental Sciences, Bareilly, Uttar Pradesh, IndiaDepartment of Oral Pathology and Microbiology, Institute of Dental Sciences, Bareilly, Uttar Pradesh, IndiaDepartment of Periodontology and Implantology, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, IndiaBackground. Various treatment modalities, such as leucocyte platelet-rich fibrin (L-PRF), bone grafts,and membranes, have been used for the restoration of lost periodontal tissues. Titanium-preparedplatelet-rich fibrin (T-PRF) has attracted attention for its proper haemocompatibility, thick fibrinmeshwork, and long resorption time. The present study aimed to evaluate the effectiveness of T-PRFand L-PRF in the management of intra-bony defects based on clinical and radiographic criteria. Methods. Twenty-six subjects with 34 intra-bony 3- walled defects were divided into two groups (n=17)and treated with T-PRF or L-PRF. Clinical and radiographic measurements were recorded at baselineand 6- , 3- and 9- month intervals and tabulated on Microsoft Excel spreadsheets. For intra- and intergroupcomparisons, paired and unpaired t-tests were performed. P<0.05 was set as statistically significant Results. Intra-group comparisons revealed statistically significant differences (P<0.05) from baseline inboth groups regarding clinical measurements. On intergroup comparison, the T-PRF group exhibited asignificantly higher defect fill compared to the L-PRF group (P<0.05). Conclusion. Within the limits of the present study, T-PRF seems to be a better alternative to L-PRF inthe treatment of intra-bony defects.https://joddd.tbzmed.ac.ir/PDF/joddd-27954bone regenerationchronic periodontitisperiodontal pocketdebridementplatelet-rich fibrin |
| spellingShingle | Shiva Shankar Gummaluri Hirak S Bhattacharya Madhusudan Astekar Shivani Cheruvu Evaluation of titanium-prepared platelet-rich fibrin and leucocyteplatelet-rich fibrin in the treatment of intra-bony defects: Arandomized clinical trial Journal of Dental Research, Dental Clinics, Dental Prospects bone regeneration chronic periodontitis periodontal pocket debridement platelet-rich fibrin |
| title | Evaluation of titanium-prepared platelet-rich fibrin and leucocyteplatelet-rich fibrin in the treatment of intra-bony defects: Arandomized clinical trial |
| title_full | Evaluation of titanium-prepared platelet-rich fibrin and leucocyteplatelet-rich fibrin in the treatment of intra-bony defects: Arandomized clinical trial |
| title_fullStr | Evaluation of titanium-prepared platelet-rich fibrin and leucocyteplatelet-rich fibrin in the treatment of intra-bony defects: Arandomized clinical trial |
| title_full_unstemmed | Evaluation of titanium-prepared platelet-rich fibrin and leucocyteplatelet-rich fibrin in the treatment of intra-bony defects: Arandomized clinical trial |
| title_short | Evaluation of titanium-prepared platelet-rich fibrin and leucocyteplatelet-rich fibrin in the treatment of intra-bony defects: Arandomized clinical trial |
| title_sort | evaluation of titanium prepared platelet rich fibrin and leucocyteplatelet rich fibrin in the treatment of intra bony defects arandomized clinical trial |
| topic | bone regeneration chronic periodontitis periodontal pocket debridement platelet-rich fibrin |
| url | https://joddd.tbzmed.ac.ir/PDF/joddd-27954 |
| work_keys_str_mv | AT shivashankargummaluri evaluationoftitaniumpreparedplateletrichfibrinandleucocyteplateletrichfibrininthetreatmentofintrabonydefectsarandomizedclinicaltrial AT hiraksbhattacharya evaluationoftitaniumpreparedplateletrichfibrinandleucocyteplateletrichfibrininthetreatmentofintrabonydefectsarandomizedclinicaltrial AT madhusudanastekar evaluationoftitaniumpreparedplateletrichfibrinandleucocyteplateletrichfibrininthetreatmentofintrabonydefectsarandomizedclinicaltrial AT shivanicheruvu evaluationoftitaniumpreparedplateletrichfibrinandleucocyteplateletrichfibrininthetreatmentofintrabonydefectsarandomizedclinicaltrial |