Pharmacokinetic Interaction Between Oltipraz and Silymarin in Rats
ABSTRACT. Purpose: To evaluate the pharmacokinetic interaction between oltipraz and silymarin after intravenous and oral administration of both drugs to male Sprague–Dawley rats. Methods: Oltipraz (single doses of 10 and 30 mg/kg for intravenous and oral administration, respectively), silymarin (sin...
Main Authors: | Min Kyung Kang, Soo Kyung Bae, Jin Wan Kim, Myung Gull Lee |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2009-02-01
|
Series: | Journal of Pharmacy & Pharmaceutical Sciences |
Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/5069 |
Similar Items
-
Elucidating the Anti-Tumorigenic Efficacy of Oltipraz, a Dithiolethione, in Glioblastoma
by: Upasana Kapoor-Narula, et al.
Published: (2022-09-01) -
Healthy supplements of silymarin and aqueous extract of Salvia miltiorrhiza on the pharmacokinetic interaction of lamivudine in rats
by: Li-Wen Chang, et al.
Published: (2015-08-01) -
Effects of Silymarin on the In Vivo Pharmacokinetics of Simvastatin and Its Active Metabolite in Rats
by: Ying Li, et al.
Published: (2019-04-01) -
The Effects of Oltipraz on Tissue Regeneration in the Process of Wound Healing: A Stereological Study
by: Ali Noorafshan, et al.
Published: (2014-10-01) -
The Effects of Oltipraz on Tissue Regeneration in the Process of Wound Healing: A Stereological Study
by: Ali Noorafshan, et al.
Published: (2014-10-01)