Centrifugal telencephalic afferent connections to the main and accessory olfactory bulbs
Parallel to the olfactory system, most mammals possess an accessory olfactory or vomeronasal system. The olfactory and vomeronasal epithelia project to the main and accessory olfactory bulbs, which in turn project to adjacent areas of the telencephalon, respectively. New data indicate that projectio...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2012-05-01
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| Series: | Frontiers in Neuroanatomy |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnana.2012.00019/full |
| _version_ | 1818959142466879488 |
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| author | Alicia eMohedanoMoriano Carlos ede la Rosa-Prieto Daniel eSaiz-Sanchez Isabel eUbeda-Banon Palma ePro-Sistiaga Miguel ede Moya-Pinilla Alino eMartinez-Marcos |
| author_facet | Alicia eMohedanoMoriano Carlos ede la Rosa-Prieto Daniel eSaiz-Sanchez Isabel eUbeda-Banon Palma ePro-Sistiaga Miguel ede Moya-Pinilla Alino eMartinez-Marcos |
| author_sort | Alicia eMohedanoMoriano |
| collection | DOAJ |
| description | Parallel to the olfactory system, most mammals possess an accessory olfactory or vomeronasal system. The olfactory and vomeronasal epithelia project to the main and accessory olfactory bulbs, which in turn project to adjacent areas of the telencephalon, respectively. New data indicate that projections arising from the main and accessory olfactory bulbs partially converge in the rostral telencephalon and are non-overlapping at caudal telencephalic levels. Therefore, the basal telencephalon should be reclassified in olfactory, vomeronasal and mixed areas. On the other hand, it has been demonstrated that virtually all olfactory- and vomeronasal-recipient structures send reciprocal projections to the main and accessory olfactory bulbs, respectively. Further, non-chemosensory recipient structures also projects centrifugally to the olfactory bulbs. These feed-back projections appear to be essential modulating processing of chemosensory information. The present work aims at characterizing centrifugal projections to the main and accessory olfactory bulbs arising from olfactory, vomeronasal, mixed and non-chemosensory recipient telencephalic areas. This issue has been addressed by using tracer injections in the rat and mouse brain. Tracer injections were delivered into the main and accessory olfactory bulbs as well as in olfactory, vomeronasal, mixed and non-chemosensory recipient telencephalic structures. The results confirm that olfactory- and vomeronasal-recipient structures project to the main and accessory olfactory bulbs, respectively. Interestingly, olfactory (e.g., piriform cortex), vomeronasal (e.g., posteromedial cortical amygdala), mixed (e.g., the medial amygdala) and non-chemosensory-recipient (e.g., the nucleus of the diagonal band) structures project to the main and to the accessory olfactory bulbs thus providing the possibility of simultaneous modulation and interaction of both systems at different stages of chemosensory processing. |
| first_indexed | 2024-12-20T11:36:56Z |
| format | Article |
| id | doaj.art-7e1704a32db145c2af60567595ad95e1 |
| institution | Directory Open Access Journal |
| issn | 1662-5129 |
| language | English |
| last_indexed | 2024-12-20T11:36:56Z |
| publishDate | 2012-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroanatomy |
| spelling | doaj.art-7e1704a32db145c2af60567595ad95e12022-12-21T19:42:05ZengFrontiers Media S.A.Frontiers in Neuroanatomy1662-51292012-05-01610.3389/fnana.2012.0001927516Centrifugal telencephalic afferent connections to the main and accessory olfactory bulbsAlicia eMohedanoMoriano0Carlos ede la Rosa-Prieto1Daniel eSaiz-Sanchez2Isabel eUbeda-Banon3Palma ePro-Sistiaga4Miguel ede Moya-Pinilla5Alino eMartinez-Marcos6Univ. Castilla-La ManchaUniversidad de Castilla-La ManchaUniversidad de Castilla-La ManchaUniversidad de Castilla-La ManchaCyceronUniversidad de Castilla-La ManchaUniversidad de Castilla-La ManchaParallel to the olfactory system, most mammals possess an accessory olfactory or vomeronasal system. The olfactory and vomeronasal epithelia project to the main and accessory olfactory bulbs, which in turn project to adjacent areas of the telencephalon, respectively. New data indicate that projections arising from the main and accessory olfactory bulbs partially converge in the rostral telencephalon and are non-overlapping at caudal telencephalic levels. Therefore, the basal telencephalon should be reclassified in olfactory, vomeronasal and mixed areas. On the other hand, it has been demonstrated that virtually all olfactory- and vomeronasal-recipient structures send reciprocal projections to the main and accessory olfactory bulbs, respectively. Further, non-chemosensory recipient structures also projects centrifugally to the olfactory bulbs. These feed-back projections appear to be essential modulating processing of chemosensory information. The present work aims at characterizing centrifugal projections to the main and accessory olfactory bulbs arising from olfactory, vomeronasal, mixed and non-chemosensory recipient telencephalic areas. This issue has been addressed by using tracer injections in the rat and mouse brain. Tracer injections were delivered into the main and accessory olfactory bulbs as well as in olfactory, vomeronasal, mixed and non-chemosensory recipient telencephalic structures. The results confirm that olfactory- and vomeronasal-recipient structures project to the main and accessory olfactory bulbs, respectively. Interestingly, olfactory (e.g., piriform cortex), vomeronasal (e.g., posteromedial cortical amygdala), mixed (e.g., the medial amygdala) and non-chemosensory-recipient (e.g., the nucleus of the diagonal band) structures project to the main and to the accessory olfactory bulbs thus providing the possibility of simultaneous modulation and interaction of both systems at different stages of chemosensory processing.http://journal.frontiersin.org/Journal/10.3389/fnana.2012.00019/fullAmygdalaCortexchemical sensesolfactory systemvomeronasal systempheromone |
| spellingShingle | Alicia eMohedanoMoriano Carlos ede la Rosa-Prieto Daniel eSaiz-Sanchez Isabel eUbeda-Banon Palma ePro-Sistiaga Miguel ede Moya-Pinilla Alino eMartinez-Marcos Centrifugal telencephalic afferent connections to the main and accessory olfactory bulbs Frontiers in Neuroanatomy Amygdala Cortex chemical senses olfactory system vomeronasal system pheromone |
| title | Centrifugal telencephalic afferent connections to the main and accessory olfactory bulbs |
| title_full | Centrifugal telencephalic afferent connections to the main and accessory olfactory bulbs |
| title_fullStr | Centrifugal telencephalic afferent connections to the main and accessory olfactory bulbs |
| title_full_unstemmed | Centrifugal telencephalic afferent connections to the main and accessory olfactory bulbs |
| title_short | Centrifugal telencephalic afferent connections to the main and accessory olfactory bulbs |
| title_sort | centrifugal telencephalic afferent connections to the main and accessory olfactory bulbs |
| topic | Amygdala Cortex chemical senses olfactory system vomeronasal system pheromone |
| url | http://journal.frontiersin.org/Journal/10.3389/fnana.2012.00019/full |
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