Inhibition of Virulence Factors and Biofilm Formation by Wogonin Attenuates Pathogenicity of <i>Pseudomonas aeruginosa</i> PAO1 via Targeting <i>pqs</i> Quorum-Sensing System

Inhibition of Virulence Factors and Biofilm Formation by Wogonin Attenuates Pathogenicity of <i>Pseudomonas aeruginosa</i> PAO1 via Targeting <i>pqs</i> Quorum-Sensing System

<i>Pseudomonas aeruginosa</i>, an important opportunistic pathogen, is capable of producing various virulence factors and forming biofilm that are regulated by quorum sensing (QS). It is known that targeting virulence factor production and biofilm formation instead of exerting selective...

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Bibliographic Details
Main Authors: Shiwei Wang, Yuqi Feng, Xiaofeng Han, Xinyu Cai, Liu Yang, Chaolan Liu, Lixin Shen
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
wogonin
<i>P. aeruginosa</i>
quorum sensing
virulence factors
biofilm
molecular docking
Online Access:https://www.mdpi.com/1422-0067/22/23/12699

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