Safety Issues With the Use of Antimicrobials in Current Clinical Practice

Due to increased use of antibiotics in current clinical practice it is very important to evaluate all risks of antimicrobial therapy. Pharmacovigilance plays a vital role in ensuring that doctors, together with the patient, have enough information about safety profile of a drug for treatment. This p...

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Main Authors: Kuzmina A.V., Polivanov V.A., Asetskaya I.L., Zyryanov S.K.
Format: Article
Language:Russian
Published: Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy 2015-05-01
Series:Клиническая микробиология и антимикробная химиотерапия
Subjects:
Online Access:https://cmac-journal.ru/publication/2015/2/cmac-2015-t17-n2-p146/cmac-2015-t17-n2-p146.pdf
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author Kuzmina A.V.
Polivanov V.A.
Asetskaya I.L.
Zyryanov S.K.
author_facet Kuzmina A.V.
Polivanov V.A.
Asetskaya I.L.
Zyryanov S.K.
author_sort Kuzmina A.V.
collection DOAJ
description Due to increased use of antibiotics in current clinical practice it is very important to evaluate all risks of antimicrobial therapy. Pharmacovigilance plays a vital role in ensuring that doctors, together with the patient, have enough information about safety profile of a drug for treatment. This paper presents some of the results from postmarketing studies of antimicrobial drugs. It shows Russian and international data of frequency and severity of adverse drug reactions to antibiotics in different patient groups, including children and older persons. Practical recommendations for safer use of antimicrobial therapy are proposed in this paper. The authors also discuss topical problems of inappropriate use of antibiotics and antibiotic resistance.
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spelling doaj.art-7e1cdef6e88e4d8ba38fa75bdd9359e22022-12-22T01:05:24ZrusInterregional Association for Clinical Microbiology and Antimicrobial ChemotherapyКлиническая микробиология и антимикробная химиотерапия1684-43862686-95862015-05-01172146156cmac-2015-t17-n2-p146Safety Issues With the Use of Antimicrobials in Current Clinical PracticeKuzmina A.V.0Polivanov V.A.1Asetskaya I.L.2Zyryanov S.K.3Information and Methodological Center for Expertise, Registration and Analysis of Medicinal Products, Moscow, RussiaInformation and Methodological Center for Expertise, Registration and Analysis of Medicinal Products, Moscow, RussiaInformation and Methodological Center for Expertise, Registration and Analysis of Medicinal Products, Moscow, RussiaRussian National Research Medical University named after N.I. Pirogov, Moscow, RussiaDue to increased use of antibiotics in current clinical practice it is very important to evaluate all risks of antimicrobial therapy. Pharmacovigilance plays a vital role in ensuring that doctors, together with the patient, have enough information about safety profile of a drug for treatment. This paper presents some of the results from postmarketing studies of antimicrobial drugs. It shows Russian and international data of frequency and severity of adverse drug reactions to antibiotics in different patient groups, including children and older persons. Practical recommendations for safer use of antimicrobial therapy are proposed in this paper. The authors also discuss topical problems of inappropriate use of antibiotics and antibiotic resistance.https://cmac-journal.ru/publication/2015/2/cmac-2015-t17-n2-p146/cmac-2015-t17-n2-p146.pdfantimicrobialsadverse drug reactionpharmacovigilanceantibiotic resistance
spellingShingle Kuzmina A.V.
Polivanov V.A.
Asetskaya I.L.
Zyryanov S.K.
Safety Issues With the Use of Antimicrobials in Current Clinical Practice
Клиническая микробиология и антимикробная химиотерапия
antimicrobials
adverse drug reaction
pharmacovigilance
antibiotic resistance
title Safety Issues With the Use of Antimicrobials in Current Clinical Practice
title_full Safety Issues With the Use of Antimicrobials in Current Clinical Practice
title_fullStr Safety Issues With the Use of Antimicrobials in Current Clinical Practice
title_full_unstemmed Safety Issues With the Use of Antimicrobials in Current Clinical Practice
title_short Safety Issues With the Use of Antimicrobials in Current Clinical Practice
title_sort safety issues with the use of antimicrobials in current clinical practice
topic antimicrobials
adverse drug reaction
pharmacovigilance
antibiotic resistance
url https://cmac-journal.ru/publication/2015/2/cmac-2015-t17-n2-p146/cmac-2015-t17-n2-p146.pdf
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AT zyryanovsk safetyissueswiththeuseofantimicrobialsincurrentclinicalpractice