Characterization of a new molecule capable of inhibiting several steps of the amyloid cascade in Alzheimer's disease

Characterization of a new molecule capable of inhibiting several steps of the amyloid cascade in Alzheimer's disease

Introduction: Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder in elderly people. Existent therapies are directed at alleviating some symptoms, but are not effective in altering the course of the disease. Methods: Based on our previous study that showed that an Aβ-inter...

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Bibliographic Details
Main Authors: Christian Peters, Denisse Bascuñán, Carlos F. Burgos, Catalina Bobadilla, Juliana González-Sanmiguel, Subramanian Boopathi, Nicolás Riffo, Eduardo J. Fernández-Pérez, María Elena Tarnok, Luis Felipe Aguilar, Wendy Gonzalez, Luis G. Aguayo
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Neurobiology of Disease
Subjects:
Alzheimer
Small molecule
Novel
Multi-step
Drug
Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120302138

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