Antagonstic Effect of Lactobacillus Fermentum Supernatant AgainstEnterococcus Faeciumand Enterococcus Faecalis In Vitro
Background:Lactobacillus fermentum selected as an alternative treatment to prevent or treat urogenital infection based on their probiotics properties and production of bacteriocins. Objective: The present work was done to study the inhibition activity of L. fermentum cell free supernatant against ur...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
College of Medicine University of Baghdad
2012-07-01
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| Series: | مجلة كلية الطب |
| Subjects: | |
| Online Access: | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/747 |
| Summary: | Background:Lactobacillus fermentum selected as an alternative treatment to prevent or treat urogenital infection based on their probiotics properties and production of bacteriocins.
Objective: The present work was done to study the inhibition activity of L. fermentum cell free supernatant against urogenital pathogens Enterococcus faecium and Enterococcus faecalisinvitro.
Materials and methods: L.fermentum isolates have been collected from vaginal swabs . A supernatant of these isolates has been prepared and its antibacterial activity against 3 isolates of E.faecium and 3 isolates of E.faecalis has been studied.
Results: Different concentrations have been prepared and the most effective one was 1000μg/ml and the most affected isolate of E.faecalis was no. 3 which its MIC was 64μg/ml and MBC was 128 μg/ml, while the most affected isolate of E. faecium was no. 1 which its MIC was 128 μg/ml and MBC was 256 μg/ml .
Conclusion:L. fermentumCFS showed significant activity against both Enterococcus isolates and showed closely related results. |
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| ISSN: | 0041-9419 2410-8057 |