Noninvasive screening tools for Down syndrome: a review
Meagan Smith, Jeannie Visootsak Emory University, Department of Human Genetics, Atlanta, GA, USA Abstract: Down syndrome is the leading cause of prenatal chromosome abnormalities, accounting for 53% of all reported chromosome conditions. Testing strategies, guidelines, and screening options have exp...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2013-03-01
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| Series: | International Journal of Women's Health |
| Online Access: | http://www.dovepress.com/noninvasive-screening-tools-for-down-syndrome-a-review-a12377 |
| _version_ | 1811310566547914752 |
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| author | Smith M Visootsak J |
| author_facet | Smith M Visootsak J |
| author_sort | Smith M |
| collection | DOAJ |
| description | Meagan Smith, Jeannie Visootsak Emory University, Department of Human Genetics, Atlanta, GA, USA Abstract: Down syndrome is the leading cause of prenatal chromosome abnormalities, accounting for 53% of all reported chromosome conditions. Testing strategies, guidelines, and screening options have expanded from their conception in the 1970s, and now include such options as anatomical ultrasound, maternal serum screening, and noninvasive prenatal testing. This review summarizes all currently available noninvasive diagnostic techniques for the detection of Down syndrome. By understanding fully each technology and the possible alternatives, the physician will be able to provide their patients with all the information necessary to make an informed decision regarding their medical management. Keywords: Down syndrome, noninvasive screening, diagnostic techniques |
| first_indexed | 2024-04-13T10:00:59Z |
| format | Article |
| id | doaj.art-7e2494f1372048068418ff12431b1681 |
| institution | Directory Open Access Journal |
| issn | 1179-1411 |
| language | English |
| last_indexed | 2024-04-13T10:00:59Z |
| publishDate | 2013-03-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of Women's Health |
| spelling | doaj.art-7e2494f1372048068418ff12431b16812022-12-22T02:51:15ZengDove Medical PressInternational Journal of Women's Health1179-14112013-03-012013default125131Noninvasive screening tools for Down syndrome: a reviewSmith MVisootsak JMeagan Smith, Jeannie Visootsak Emory University, Department of Human Genetics, Atlanta, GA, USA Abstract: Down syndrome is the leading cause of prenatal chromosome abnormalities, accounting for 53% of all reported chromosome conditions. Testing strategies, guidelines, and screening options have expanded from their conception in the 1970s, and now include such options as anatomical ultrasound, maternal serum screening, and noninvasive prenatal testing. This review summarizes all currently available noninvasive diagnostic techniques for the detection of Down syndrome. By understanding fully each technology and the possible alternatives, the physician will be able to provide their patients with all the information necessary to make an informed decision regarding their medical management. Keywords: Down syndrome, noninvasive screening, diagnostic techniqueshttp://www.dovepress.com/noninvasive-screening-tools-for-down-syndrome-a-review-a12377 |
| spellingShingle | Smith M Visootsak J Noninvasive screening tools for Down syndrome: a review International Journal of Women's Health |
| title | Noninvasive screening tools for Down syndrome: a review |
| title_full | Noninvasive screening tools for Down syndrome: a review |
| title_fullStr | Noninvasive screening tools for Down syndrome: a review |
| title_full_unstemmed | Noninvasive screening tools for Down syndrome: a review |
| title_short | Noninvasive screening tools for Down syndrome: a review |
| title_sort | noninvasive screening tools for down syndrome a review |
| url | http://www.dovepress.com/noninvasive-screening-tools-for-down-syndrome-a-review-a12377 |
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