Tau and Aβ42 in lavage fluid of pneumonia patients are associated with end-organ dysfunction: A prospective exploratory study.

Tau and Aβ42 in lavage fluid of pneumonia patients are associated with end-organ dysfunction: A prospective exploratory study.

<h4>Background</h4>Bacterial pneumonia and sepsis are both common causes of end-organ dysfunction, especially in immunocompromised and critically ill patients. Pre-clinical data demonstrate that bacterial pneumonia and sepsis elicit the production of cytotoxic tau and amyloids from pulmo...

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Main Authors: Phoibe Renema, Jean-Francois Pittet, Angela P Brandon, Sixto M Leal, Steven Gu, Grace Promer, Andrew Hackney, Phillip Braswell, Andrew Pickering, Grace Rafield, Sarah Voth, Ron Balczon, Mike T Lin, K Adam Morrow, Jessica Bell, Jonathon P Audia, Diego Alvarez, Troy Stevens, Brant M Wagener
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0298816

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